Results 11 to 20 of about 532,890 (258)

Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

Nature reviews. Drug discovery, 2021
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains challenging to treat owing to the limited response to available therapies.
T. Bieber
semanticscholar   +1 more source

Molecular Mechanisms of Atopic Dermatitis Pathogenesis

International Journal of Molecular Sciences, 2021
Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic feature is persistent itching of the skin. The chronic, relapsing course of the disease, economic burden, and the whole family’s involvement in the treatment process ...
Jowita Sroka-Tomaszewska, M. Trzeciak
semanticscholar   +1 more source

Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*

British Journal of Dermatology, 2020
Tralokinumab, a fully human monoclonal antibody, specifically neutralizes interleukin‐13, a key cytokine driving peripheral inflammation in atopic dermatitis (AD). In phase II studies, tralokinumab combined with topical corticosteroids provided early and
A. Wollenberg, A. Blauvelt, E. Guttman‐Yassky, M. Worm, C. Lynde, J. Lacour, L. Spelman, N. Katoh, H. Saeki, Yves Poulin, A. Lesiak, L. Kircik, S. H. Cho, P. Herranz, M. Cork, Ketty Peris, L. Steffensen, B. Bang, A. Kuznetsova, T. N. Jensen, M. L. Østerdal, E. Simpson   +21 more
semanticscholar   +1 more source

Prevalence and Incidence of Atopic Dermatitis: A Systematic Review

Acta Dermato-Venereologica, 2020
The primary objective of this study was to systematically review and analyse epidemiological studies of the prevalence and incidence of atopic dermatitis (AD) during childhood and adulthood, focusing on data from the 21st century.
Simon B A Bylund, L. V. von Kobyletzki, Marika Svalstedt, Å. Svensson   +3 more
semanticscholar   +1 more source

Diagnostic Features of Atopic Dermatitis

Acta Dermato-Venereologica, 1980
is missing.
J. Hanifin, G. Rajka
semanticscholar   +1 more source

Role of genetic aspect in pathogenesis of atopic dermatitis [PDF]

, 2013
The pathogenesis of atopic dermatitis (AD) is a very complicated process that involves an intricate array of molecules. Nowadays it is generally accepted that cytokines play an important role in the progression of the clinical presentation of atopic ...
Wesserling Martyna
core   +1 more source

First findings of ulcerative and necrotizing dermatitis in olive ridley turtles (Lepidochelys olivacea) in La Escobilla, Oaxaca, Mexico

Ciencias Marinas, 2023
Ulcerative and necrotizing dermatitis (UND) is a cutaneous disease caused by traumatic skin lesions on the necks of sea turtles. In this study we report the first findings of UND in free-ranging olive ridley turtles (Lepidochelys olivacea) in La ...
Alejandra Buenrostro-Silva, Jesús García-Grajales, Petra Sánchez-Nava, María de Lourdes Ruíz-Gómez   +3 more
doaj   +1 more source

Treatment of estrogen-induced dermatitis with omalizumab [PDF]

, 2019
In 1945, Drs Bernhard Zondek and Yehuda Bromberg demonstrated intradermal treatment with estrone and estradiol benzoate induced urticarial lesions in some patients.1 Fifty years later, Shelley et al,2 who introduced the concept of progesterone dermatitis
Baker, William H., Bell, Maria C., Heskett, Jordan B., Mousdicas, Nico, Ocana, Jesus A., Turner, Matthew J.   +5 more
core   +1 more source

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.

New England Journal of Medicine, 2016
BACKGROUND Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be important drivers of atopic or allergic diseases such as atopic dermatitis ...
E. Simpson, T. Bieber, E. Guttman‐Yassky, L. Beck, A. Blauvelt, M. Cork, J. Silverberg, M. Deleuran, Y. Kataoka, J. Lacour, K. Kingo, M. Worm, Y. Poulin, A. Wollenberg, Y. Soo, N. Graham, G. Pirozzi, B. Akinlade, H. Staudinger, V. Mastey, L. Eckert, A. Gadkari, N. Stahl, G. Yancopoulos, M. Ardeleanu   +24 more
semanticscholar   +1 more source

Formaldehyde-releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde-releasers [PDF]

, 2009
This is one of series of review articles on formaldehyde and formaldehyde-releasers (others: formaldehyde in cosmetics, in clothes and in metalworking fluids and miscellaneous).
Aalto-Korte, Aalto-Korte, Agner, Akyol, Albert, Andersen, Andersen, Benassi, Bergh, Bergh, Brasch, Britton, Bruynzeel, Carlsen, Cohen, Cronin, Dahlquist, Dahlquist, Davis, De Groot, Emeis, Engelhardt, Epstein, Feinhman, Feinman, Fiedler, Fischer, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Flyvholm, Fransway, Fransway, Fregert, Fregert, Freireich-Astman, Geier, Geier, Geier, Gollhausen, Goossens, Gruvberger, Gruvberger, Gryllaki-Berger, Gryllaki-Berger, Hamann, Hasan, Henriks-Eckerman, Herbert, Hogan, Horsfall, Isaksson, Jacab, Jong, Jordan, Kang, Karlberg, Kränke, Lazarov, Le Coz, Lindberg, Liu, Machovcova, Maibach, Marks, Marks, Marks, Marks, Matura, Noiesen, Owen, Pasad, Perrenoud, Pratt, Rastogi, Rastogi, Rietschel, Sainio, Sanchez, Sasseville, Scheman, Schnuch, Schnuch, Schnuch, Selim, Shaffer, Sugai, Tanaka, Tegner, Timmer, Trattner, Uter, Uter, Uter, Vestey, Wetter, Worm, Zachariae, Zimerson   +105 more
core   +7 more sources