Results 21 to 30 of about 518,303 (373)

Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*

open access: yesBritish Journal of Dermatology, 2020
Tralokinumab, a fully human monoclonal antibody, specifically neutralizes interleukin‐13, a key cytokine driving peripheral inflammation in atopic dermatitis (AD). In phase II studies, tralokinumab combined with topical corticosteroids provided early and
A. Wollenberg   +21 more
semanticscholar   +1 more source

Changes in connexin 43 in inflammatory skin disorders: Eczema, psoriasis, and Steven‐Johnson syndrome/toxic epidermal necrolysis

open access: yesHealth Science Reports, 2021
Background Connexin 43 (Cx43) plays a central role in the inflammatory response and wound healing. Targeting Cx43 expression reduces inflammation in a variety of injuries.
Mandy L. L. Tan   +5 more
doaj   +1 more source

Prevalence and Incidence of Atopic Dermatitis: A Systematic Review

open access: yesActa Dermato-Venereologica, 2020
The primary objective of this study was to systematically review and analyse epidemiological studies of the prevalence and incidence of atopic dermatitis (AD) during childhood and adulthood, focusing on data from the 21st century.
Simon B A Bylund   +3 more
semanticscholar   +1 more source

Shrinkage estimation for dose-response modeling in phase II trials with multiple schedules [PDF]

open access: yesStatistics in Biopharmaceutical Research, 2020, 2020
Recently, phase II trials with multiple schedules (frequency of administrations) have become more popular, for instance in the development of treatments for atopic dermatitis. If the relationship of the dose and response is described by a parametric model, a simplistic approach is to pool doses from different schedules.
arxiv   +1 more source

Allergic contact dermatitis from sculptured acrylic nails: special presentation with an airborne pattern

open access: yesDermatology Reports, 2012
Methylmethacrylate was first reported in 1941 as a cause of contact dermatitis. Since then, occupational contact allergies to acrylates in dentistry, orthopedic surgery, printing industry and industry have been reported, but few reports are found in the ...
Paula Maio   +4 more
doaj   +1 more source

Granuloma caused by Acanthocheilonema spp. in a canine - case report [PDF]

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
A canine patient, 13-year-old mixed breed male, 24kg, was seen at a private clinic in the city of Guayaquil, Ecuador. The main reason for consultation was the evaluation of a mass in the right knee and neck that had previously been cytologically ...
A.R.O. Palacios   +7 more
doaj   +1 more source

Diagnostic Features of Atopic Dermatitis

open access: yesActa Dermato-Venereologica, 1980
is missing.
J. Hanifin, G. Rajka
semanticscholar   +1 more source

Efficacy and Safety of Abrocitinib in Patients With Moderate-to-Severe Atopic Dermatitis

open access: yesJAMA dermatology, 2020
This randomized clinical trial investigates the efficacy and safety of abrocitinib in adolescents and adults with moderate-to-severe atopic dermatitis.
J. Silverberg   +10 more
semanticscholar   +1 more source

Yeast fungi of the genus Malassezia in dermatological diseases in animals [PDF]

open access: yesНауковий вісник ветеринарної медицини, 2021
The relevance of a comprehensive study of yeast fungi of the genus Malassezia and the development of modern methods for the diagnosis of diseases caused by small domestic animals. Infectious diseases of small domestic animals caused by yeasts have become
Arkhypenko A., Ushkalov V.
doaj   +1 more source

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be important drivers of atopic or allergic diseases such as atopic dermatitis ...
E. Simpson   +24 more
semanticscholar   +1 more source

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