Results 51 to 60 of about 532,890 (258)

Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: A pivotal interplay in the pathogenesis of Atopic Dermatitis [PDF]

, 2018
Individuals with Atopic dermatitis (AD) are highly susceptible to Staphylococcus aureus colonization. However, the mechanisms driving this process as well as the impact of S. aureus in AD pathogenesis are still incompletely understood.
A Matlow, A Oliveira de, A Sandilands, A Sonesson, AC Krakowski, AD Irvine, AM Bowcock, B Cabanillas, B Han, BC Friedman, C Fux, C Pascolini, CI Ewing, CL Jinnestal, D Ellinghaus, D Lebeaux, DY Koller, DYM Leung, DYM Leung, E Clark, E Weinberg, EC Clark, EG Domenico Di, EG Domenico Di, FJ Bath-Hextall, FR Menegotto, G Stinco, GF Gad, GL Hazelbauer, GM O’Regan, GM O’Regan, GU Meduri, H Akiyama, HB Allen, HH Kong, I Marenholz, I Nomura, J Oh, J Schmitt, JH Lee, JM Hanifin, JQ Gong, K Becker, K Breuer, K Krause, KL Hon, L Chronopoulou, L Paternoster, LA O’Neill, LP Girard, M Bhattacharya, M Denis, M Mehrotra, M Niebuhr, MD Howell, ML Schuttelaar, MS Haque, P Castaneda, P Chavant, PH Hoeger, R Lever, R Saginur, RA McLaughlin, RL Gallo, RM Klevens, RP Howlin, S Eriksson, S Kanangat, S Kezic, S Kezic, S Stutte, S Weidinger, SE Hill, SE Satorres, SE Satorres, SH Cho, SH Hung, SJ Gilani, SX Xu, T Bieber, T Biedermann, T Kobayashi, T Nakatsuji, T Werfel, TX Nhan, UG Meduri, V Dossow von, W Abramovits, Z Ikezawa   +88 more
core   +1 more source

Peak Pruritus Numerical Rating Scale: psychometric validation and responder definition for assessing itch in moderate‐to‐severe atopic dermatitis†

British Journal of Dermatology, 2019
Moderate‐to‐severe atopic dermatitis (AD) is a chronic disease characterized by intense, persistent and debilitating itch, resulting in sleep deprivation, signs of anxiety and depression, impaired quality of life and reduced productivity.
Gil Yosipovitch, M. Reaney, V. Mastey, Laurent Eckert, A. Abbe, Lauren Nelson, M. Clark, N. Williams, Zhen Chen, M. Ardeleanu, B. Akinlade, N. Graham, G. Pirozzi, H. Staudinger, S. Plaum, Allen Radin, A. Gadkari   +16 more
semanticscholar   +1 more source

A Little Experience Goes a Long Way: Chlormethine/Mechlorethamine Treatment Duration as a Function of Clinician-Level Patient Volume for Mycosis Fungoides Cutaneous T-Cell Lymphoma (MF-CTCL)—A Retrospective Cohort Study

Frontiers in Medicine, 2021
Topical chlormethine yields high response rates in mycosis fungoides cutaneous T-cell lymphoma with early discontinuation often attributed to skin reactions.
Christiane Querfeld, Theresa Pacheco, Bradley Haverkos, Gary Binder, James Angello, Brian Poligone   +5 more
doaj   +1 more source

Overweight and obese patients with nickel allergy have a worse metabolic profile compared to weight matched non-allergic individuals [PDF]

, 2018
A lack of balance between energy intake and expenditure due to overeating or reduced physical activity does not seem to explain entirely the obesity epidemic we are facing, and further factors are therefore being evaluated.
Basciani, S, Costantini, D, De Giorgi, F, GANGITANO, ELENA, Gnessi, L, Lubrano, C., Mariani, S, Masieri, S, PETRANGELI, Elisa, Poggiogalle, E, Tozzi, R, Tuccinardi, D, WATANABE, MIKIKO   +12 more
core   +1 more source

IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis. [PDF]

, 2020
Dupilumab is a fully human antibody to interleukin-4 receptor α that improves the signs and symptoms of moderate to severe atopic dermatitis (AD). To determine the effects of dupilumab on Staphylococcus aureus colonization and microbial diversity on the ...
Ardeleanu, Marius, Bissonnette, Robert, Callewaert, Chris, Gallo, Richard L, Graham, Neil MH, Guttman-Yassky, Emma, Hamilton, Jennifer D, Hultsch, Thomas, Knight, Rob, Kosciolek, Tomasz, Kotol, Paul, Krueger, James, Menter, Alan, Nakatsuji, Teruaki, Pirozzi, Gianluca, Silverberg, Jonathan I, Vrbanac, Alison   +16 more
core   +2 more sources

Microbe-host interplay in atopic dermatitis and psoriasis

Nature Communications, 2019
Despite recent advances in understanding microbial diversity in skin homeostasis, the relevance of microbial dysbiosis in inflammatory disease is poorly understood.
N. Fyhrquist, Gareth Muirhead, S. Prast-Nielsen, M. Jeanmougin, P. Oláh, T. Skoog, Gerome Jules-Clement, Micha Feld, Mauricio Barrientos-Somarribas, H. Sinkko, E. H. van den Bogaard, P. Zeeuwen, G. Rikken, J. Schalkwijk, H. Niehues, W. Däubener, S. Eller, H. Alexander, D. Pennino, S. Suomela, Ioannis Tessas, E. Lybeck, A. Baran, H. Darban, R. S. Gangwar, U. Gerstel, Katharina Jahn, Piia Karisola, L. Yan, B. Hansmann, S. Katayama, S. Meller, M. Bylesjö, P. Hupé, F. Levi‐Schaffer, Dario Greco, A. Ranki, J. Schröder, J. Barker, J. Kere, S. Tsoka, A. Lauerma, V. Soumelis, F. Nestle, B. Homey, B. Andersson, H. Alenius   +46 more
semanticscholar   +1 more source

Oxidative Stress and Atopic Dermatitis

Antioxidants, 2020
Atopic dermatitis is a common chronic/chronically relapsing inflammatory skin disease, with increasing worldwide prevalence. Etiopathogenesis is complex and multifactorial, with a mix of genetic, immunological and environmental aspects.
L. Bertino, F. Guarneri, S. Cannavò, M. Casciaro, G. Pioggia, S. Gangemi   +5 more
semanticscholar   +1 more source

Dermatoses in the elderly: Clinico-demographic profile of patients attending a tertiary care centre

Indian Journal of Dermatology, 2021
Background: Elderly population is vulnerable to develop a multitude of dermatological diseases, owing to comorbidities and polypharmacies. Objective: To know the prevalence of dermatological conditions in elderly patients attending outpatient department,
Dhiraj Kumar, Anupam Das, Debabrata Bandyopadhyay, Satyendra N Chowdhury, Nilay K Das, Preeti Sharma, Amit Kumar   +6 more
doaj   +1 more source

Nickel allergy and allergic contact dermatitis: A clinical review of immunology, epidemiology, exposure, and treatment

Contact Dermatitis, 2019
Nickel is the most frequent cause of contact allergy worldwide and has been studied extensively. This clinical review provides an updated overview of the epidemiology, exposure sources, methods for exposure quantification, skin deposition and penetration,
M. G. Ahlström, J. P. Thyssen, Michael Wennervaldt, T. Menné, J. Johansen   +4 more
semanticscholar   +1 more source

Unbearable wearables [PDF]

, 2019
As wearable devices play an increasing role in the management of health and disease, adverse skin reactions to wearables have become more common. However, the management of allergic contact dermatitis is challenging and new treatment options more ...
Hayward, Elizabeth May, Leung, Thomas H, Rosenbach, Misha, Wei, Jenny J   +3 more
core