Results 81 to 90 of about 229,471 (318)

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Advanced Pharmacological Treatment of Atopic Dermatitis [PDF]

, 2023
Atopic Dermatitis (AD) is a non-infectious, chronic, recurrent, inflammatory skin disease. The cause of AD is complex and multidimensional, and the disease manifests differently in each individual.
Hanspal, Sidak
core  

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone [PDF]

, 2018
Background Sensitivity to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) has increased rapidly over recent years. This increase is mainly related to the extensive use of high concentrations of MI in cosmetic products, although a growing ...
Gabriel Marrero-Alemán, Liuti, Federica, Pedro Saavedra Santana, Leopoldo Borrego, Noelia Hernández, López-Jiménez, Esmeralda, Saavedra Santana, Pedro, Hernández, Noelia, Federica Liuti, Esmeralda López-Jiménez, Borrego, Leopoldo, Marrero-Alemán, Gabriel   +11 more
core   +1 more source

Pellagra, a re-emerging disease: a case report of a girl from a community ravaged by insurgency

The Pan African Medical Journal, 2019
Pellagra is a nutritional disorder of niacin deficiency which is characterized by triad of dermatitis, diarrhea and dementia. It is often seen in a state of poor nutrition among alcoholics, homeless and patients suffering from malabsorption.
Ahmadu Baba Usman, Pembi Emmanuel, Dogo Belmont Manchan, Akoma chinyere, Ovansa Emmanuel Onimisi, Mava Yakubu, Kenji Hirayama   +6 more
doaj   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

New treatments of atopic dermatitis [PDF]

, 2023
Millions of people worldwide are afflicted by atopic dermatitis (AD), a common chronic inflammatory skin disease with an unpredictable clinical course. While traditional treatments have been effective for some patients, there is a need for new therapies ...
Eom, Ji One
core  

Evodiamine Alleviates 2,4-Dinitro-1-Chloro-Benzene-Induced Atopic Dermatitis-like Symptoms in BALB/c Mice

Life
Evodiamine is an alkaloid found in Evodia fruits, a traditional Chinese medicine. Preclinical studies have demonstrated its anti-inflammatory and neuroprotective properties.
So-Young Han, Dong-Soon Im
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Allergic contact dermatitis due to 1,6-hexanediol diacrylate in ostomy patients [Elektronisk resurs] [PDF]

Background: Many people live with ostomies after life-saving surgery. Ostomy patients often suffer from peristomal dermatitis. Allergic contact dermatitis (ACD) has been reported, mostly due to contact allergy (CA) to topical agents.
Svedman, Cecilia,, Dahlin, Jakob,, Mowitz, Martin,, Hamnerius, Nils,, Lund University., Siemund, Ingrid,   +5 more
core   +1 more source