Results 81 to 90 of about 228,636 (318)

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis

, 2017
Contact sensitization is common and affects up to 20% of the general population. The clinical manifestation of contact sensitization is allergic contact dermatitis. This is a clinical expression that is sometimes difficult to distinguish from other types
Teresa Berents, Suomela, Sari, Thyssen, Jacob P., Jurakić-Tončic, R., Khnykin, D., Brandner, Johanna, Maja-Lisa Clausen, Hermann-Josef Thierse, John, S.M., Molin, S., Brandner, J., Edith Hummler, Molin, Sonja, Clausen, Maja Lisa, Denis Khnykin, Koppes, S.A., Suomela, S., John, Swen M., Martin, Stefan F., Berents, T., Hummler, Edith, Jurakić-Tončic, Ružica, Agner, Tove, Angelova-Fischer, Irena, Kezic, Sanja, Kristiane A. Engebretsen, Sonja Molin, Sanja Kezic, Jakasa, Ivone, Tove Agner, Engebretsen, K.A., Brans, Richard, Ivone Jakasa, Brans, R., Angelova-Fischer, I., Kezic, S., Thierse, H.J., Johanna Brandner, Engebretsen, Kristiane A., Hummler, E., Clausen, Maja-Lisa, Stefan F. Martin, Thyssen, J.P., Khnykin, Denis, Thierse, Hermann-Josef, Thierse, Hermann Josef, Richard Brans, Jakasa, I., Swen M. John, Clausen, M.L., Sjors A. Koppes, Martin, S.F., Holm, J.O., Jacob P. Thyssen, Jan O. Holm, Holm, Jan O., Ružica Jurakić-Tončic, Koppes, Sjors A., Irena Angelova-Fischer, Sari Suomela, Agner, T., Berents, Teresa   +61 more
core   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Occupational allergic contact dermatitis caused by isocyanates

, 2002
Between 1978 and 2001, 22 patients were diagnosed with occupation-related allergic contact dermatitis from isocyanates and/or polyurethanes in our clinic .
Bruze, Magnus,, Detienne, T, Goossens, A, Lund University.   +3 more
core   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Human Fibroblast‐Myeloid cell tissue atlas across lung, synovium, skin and heart

Arthritis &Rheumatology, Accepted Article.
Background The availability of single‐cell RNA sequencing (scRNAseq data) in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Infection with Possible Novel Parapoxvirus in Horse, Finland, 2013

Emerging Infectious Diseases, 2016
A horse in Finland exhibited generalized granulomatous inflammation and severe proliferative dermatitis. After euthanization, we detected poxvirus DNA from a skin lesion sample.
Niina Airas, Maria Hautaniemi, Pernilla Syrjä, Anna Knuuttila, Niina Putkuri, Lesley Coulter, Colin J. McInnes, Olli Vapalahti, Anita Huovilainen, Paula M. Kinnunen   +9 more
doaj   +1 more source

Allergic Contact Dermatitis to Shin Pads in a Hockey Player : Acetophenone Is an Emerging Allergen

, 2019
Acetophenone azine (AA) has recently been identified as a new allergen in shin pads and sports shoes. We report the case of a boy with allergic contact dermatitis of the shins caused by AA present in his shin pads.
Bergendorff, Ola, Orton, David,, Orton, David, Ola Bergendorff, Bergendorff, Ola,, Bruze, Magnus, Koumaki, Dimitra, Bruze, Magnus,, Dimitra Koumaki, David Orton, Koumaki, Dimitra,, Magnus Bruze, Lund University.   +12 more
core   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source