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Dermatofibrosarcoma protuberans.
Dermatofibrosarcoma protuberans (DFSP) is a relatively unusual, locally aggressive cutaneous tumor of intermediate malignancy, that most frequently occurs with a slight predominance in young adult men on the trunk and proximal extremities. It arises from the dermis and invades deeper subcutaneous tissues (fat, fascia, muscle, bone), but, despite its ...
DE PASQUALE, Rocco +4 more
core +4 more sources
Dermatofibrosarcoma protuberans
El Dermatofibrosarcoma Protuberans (DFS) es un tumor de piel, de etiología aún no determinada. Es localmente maligno y de crecimiento lento. En la mayoría de los casos se presentan recidivas posteriores a la resección quirúrgica y en raras ocasiones ...
Maria Leone +3 more
doaj +3 more sources
Dermatofibrosarcoma protuberans is a rare dermal and subcutaneous soft‐tissue tumor, uncommon in children, characterized by CD34 positivity and COL1A1‐PDGFB fusion. Prognosis is generally good, but local recurrence risk is high, so complete excision with
Sima Shamshiri Khamene +3 more
doaj +2 more sources
A rare case of dermatofibrosarcoma protuberans of the forefoot [PDF]
Dermatofibrosarcoma protuberans is an extremely rare, potentially malignant tumor type that usually presents on the trunk or proximal extremities. The clinical presentation includes a gradually enlarging painless plaque-like or nodular lesion of the skin
Cameron Wales +4 more
doaj +2 more sources
Dermatofibrosarcoma protuberans [PDF]
Hombre de 20 años de edad, con lesión tumoral en tercio medio de antebrazo derecho de 3 meses de evolución. Por los hallazgos clínicopatológicos se hace diagnóstico de dermatofibrosarcoma protuberans de tipo mixoide.
Sandra Helena Yepes R. +3 more
doaj +1 more source
Dermatofibrosarcoma protuberans
Dermatofibrosarcoma protuberans (DFSP) is a slow growing tumor with a very low metastatic potential but with significant subclinical extension and great capacity for local destruction. Thus, the first surgeon approached with such challenging tumor must attempt to cure the patient with a method that spares healthy tissue and ensures an optimal ...
Shashikant Malkud, Veeresh Dyavannanavar
doaj +5 more sources
Dermatofibrosarcoma protuberans [PDF]
Dermatofibrosarcoma protuberans is the most common skin sarcoma, although its incidence is very low compared with other skin tumors. It presents as a slow-growing indurated plaque on which nodules develop over time. The lesion arises in the dermis but can invade subcutaneous tissue, fascia, muscle and even bone.
C, Serra-Guillén +2 more
openaire +4 more sources
MRI-Based Surgical Margin Assessment in Dermatofibrosarcoma Protuberans: Correlation With Pathological Extent. [PDF]
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive cutaneous tumor characterized by infiltrative growth and a high risk of local recurrence if incompletely excised. Although Mohs micrographic surgery is recommended, wide local excision (WLE) remains widely used in clinical practice; however, the clinical utility of preoperative ...
Kito M +11 more
europepmc +2 more sources
Angiogenic and Stromal Remodeling Associated With Aggressive Fibrosarcomatous Dermatofibrosarcoma Protuberans [PDF]
FS‐DFSP exhibits coordinated angiogenic and stromal remodeling characterized by immature vascular features, CAF accumulation, and enhanced macrophage infiltration. VEGFA, CCL2, and CXCR4 may contribute to this tumor‐promoting microenvironment. ABSTRACT Although collagen type 1 alpha 1 (COL1A1)–platelet‐derived growth factor B‐chain (PDGFB) gene fusion ...
Shiraishi S +11 more
europepmc +2 more sources
Clinical insights into dermatofibrosarcoma protuberans [PDF]
Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive cutaneous soft tissue sarcoma, it is the second most common skin sarcoma after Kaposi's sarcoma. The cause of DFSP remains unknown.
Arias, Francisco J. C. +4 more
core +1 more source

