Results 91 to 100 of about 3,318,202 (320)

Characterizing local and systemic exposure to clobetasol propionate in healthy subjects and patients with atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims There is a potential risk of systemic side‐effects with the use of potent corticosteroids, such as clobetasol propionate (CP). This concern is of particular interest in paediatric patients. The aim of this study was to develop and verify a physiologically based pharmacokinetic (PBPK) model to describe the local and systemic exposure to CP
Janna K. Duong   +6 more
wiley   +1 more source

Psoriasis in the Era of Targeted Cancer Therapeutics: A Systematic Review on De Novo and Pre-existing Psoriasis in Oncologic Patients Treated with Emerging Anti-neoplastic Agents

open access: yesDermatology and Therapy
New advancements in medicine have paved the way for targeted therapies and immune checkpoint inhibitors (ICIs), which have become mainstays of cancer therapy.
Vrinda Madan   +5 more
doaj   +1 more source

Dapson in the Treatment of Pyoderma Gangrenosum: a Narrative Review

open access: yesPrzegląd Dermatologiczny
Pyoderma gangrenosum is a rare but highly debilitating dermatologic condition frequently associated with systemic disorders such as inflammatory bowel disease and rheumatoid arthritis.
Paweł Głuszak   +5 more
doaj   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière   +13 more
wiley   +1 more source

Association of cetuximab with adverse pulmonary events in cancer patients: a comprehensive review

open access: yesJournal of Experimental & Clinical Cancer Research, 2009
Compounds derived from biologic sources, or biologicals, are increasingly utilized as therapeutic agents in malignancy. Development of anti-cancer targeted therapies from biologics is increasingly being utilized. Cetuximab, a chimeric monoclonal antibody,
Lu Jason   +5 more
doaj   +1 more source

Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for
Ditte Resendal Gotfredsen   +5 more
wiley   +1 more source

Liposomes and Other Nanocarriers for the Treatment of Acne Vulgaris: Improved Therapeutic Efficacy and Skin Tolerability

open access: yesPharmaceutics
Acne vulgaris is a common dermatologic disorder that affects approximately 85% of teenagers, which significantly impacts the quality of life in adolescents. It is a chronic disease of the sebaceous follicles that is multifactorial in etiology.
Nina Dragicevic, Howard I. Maibach
doaj   +1 more source

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