Results 91 to 100 of about 28,985 (310)

Time to Onset of Action for Biologics and Targeted Treatments in Psoriasis: Systematic Targeted Literature Review and Network Meta-Analysis

Dermatology and Therapy
Introduction For some patients with plaque psoriasis (PsO), a rapid response (i.e. short interval to time to onset of action [TOA]) is desired. The primary objective was to determine average time to achieve a Psoriasis Area and Severity Index (PASI) 90 ...
Kim A. Papp, Ron Vender, Kerri Purdy, Fiona Lovegrove, Irina Oroz, Parbeer Grewal, Perla Lansang, Laura Park-Wyllie, Nastaran Abbarin, Ya-Wen Yang, Becky Hooper, Sandra Vigelis, Tim Disher, Richard G. Langley   +13 more
doaj   +1 more source

Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force [PDF]

, 2013
Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment
Baraliakos, Xenofon, Betteridge, Neil, Braun, Jürgen, Burgos-Vargas, Ruben, Collantes-Estevez, Eduardo, de Wit, Martinus, Deodhar, Atul, Dougados, Maxime, Elewaut, Dirk, Emery, Paul, FitzGerald, Oliver, Gossec, Laure, Helliwell, Philip, Jongkees, Merryn, Kavanaugh, Arthur, Kvien, Tore K, Landewé, Robert, Luger, Thomas, Maccarone, Mara, Mease, Philip, Olivieri, Ignazio, Redlich, Kurt, Reveille, John, Ritchlin, Christopher, Rudwaleit, Martin, Schoels, Monika, Sieper, Joachim, Smolen, Josef S, Van den Bosch, Filip, van der Heijde, Désirée, Wei, James Cheng-Chung, Winthrop, Kevin   +31 more
core   +2 more sources

Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study

Annals of Neurology, EarlyView.
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim, Trond Riise, Marianna Cortese, Ola Nakken, Ole‐Bjørn Tysnes, Jannicke Igland, Kjetil Bjornevik   +6 more
wiley   +1 more source

[Immunosuppressive agents in Dermatology].

Anais brasileiros de dermatologia, 2010
Immunosupressants are drugs that act in cell division and have anti-inflammatory effects. Therefore, they are essentially prescribed in the prevention of transplant rejection and in the treatment of autoimmune disorders and chronic inflammatory diseases, whose main example in Dermatology is psoriasis.
Aline Lopes, Bressan, Roberto Souto da, Silva, Elisa, Fontenelle, Alexandre Carlos, Gripp   +3 more
openaire   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

A Case Series of Different Cutaneous Adverse Drug Reactions Attending the Dermatology Clinic of a Tertiary Care Center [PDF]

Bengal Physician Journal
Background: Cutaneous adverse drug reactions (CADRs) constitute a heterogeneous array of immunologically and non-immunologically mediated dermatologic sequelae secondary to pharmacologic exposure. These entities encompass Type I (IgE-mediated anaphylaxis)
Debalina Kanjilal, Suhena Sarkar, Abanti Saha, Birupaksha Biswas, Soutrik Roy   +4 more
doaj   +1 more source

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting. [PDF]

, 2015
PurposeTo determine the incidence of chemotherapy-induced nausea/vomiting (CINV) and chemotherapy treatment delay and adherence among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.Materials ...
Grabner, Michael, Palli, Swetha Rao, Quimbo, Ralph A, Rugo, Hope S   +3 more
core   +2 more sources

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer [PDF]

, 2011
Tyrosine kinase inhibitors (TKIs) which target angiogenesis are promising treatments for patients with metastatic medullary and differentiated thyroid cancers.
Jean-Bernard Durand, Maria E. Cabanillas, Mimi I. Hu, Naifa L. Busaidy   +3 more
core   +1 more source

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
wiley   +1 more source