Results 161 to 170 of about 24,890 (241)

Clinical Characteristics and Safety Profiles of Japanese Psoriasis Patients Who Continued Apremilast Treatment for 6 and 12 Months: A Post Hoc Analysis of an Apremilast Postmarketing Surveillance Study

The Journal of Dermatology, EarlyView.
ABSTRACT Apremilast is a phosphodiesterase 4 inhibitor approved for moderate to severe psoriasis in Japan. Apremilast significantly improved Physician's Global Assessment (PGA) and Dermatology Life Quality Index (DLQI) both at 6 and 12 months in a previously published primary post‐surveillance study.
Mamitaro Ohtsuki, Yukari Okubo, Hidehisa Saeki, Atsuyuki Igarashi, Shinichi Imafuku, Masatoshi Abe, Katsuya Saito, Ryuichi Ogawa, Akimichi Morita   +8 more
wiley   +1 more source

Management of Patients with IBD and History of Cancer. [PDF]

Cancers (Basel)
Faggiani I, Bencardino S, Allocca M, Furfaro F, Zilli A, Parigi TL, Cicerone C, Solitano V, Peyrin-Biroulet L, Danese S, D'Amico F.   +10 more
europepmc   +1 more source

Clocking Injustice: Racial Disparities in Specialty Wait Times

Health Services Research, EarlyView.
ABSTRACT Objective Timely access to care is associated with improved morbidity, mortality, and quality of life, making disparate access to specialty care a potential contributor to racial inequities in health outcomes. In this nationwide analysis, we quantified specialty care waits by race and ethnicity and identified potential drivers of observed ...
Daniel A. Asfaw, Sarah H. Gordon, Michael Anne Kyle, Kevin N. Griffith   +3 more
wiley   +1 more source

Use of oral retinoids in the perioperative period by surgical specialty: a literature review. [PDF]

Arch Dermatol Res
Truax L, Hendrixson M, Naqvi J, Trevino J.   +3 more
europepmc   +1 more source

MMF Is an Effective and Safer Treatment Options for Treatment‐Naïve Patients With Autoimmune Hepatitis Compared to Azathioprine: A Systematic Review and Meta‐Analysis

Journal of Digestive Diseases, EarlyView.
Mycophenolate mofetil (MMF) demonstrates superior efficacy and tolerability compared to azathioprine (AZA) in treatment‐naïve autoimmune hepatitis (AIH) patients. Meta‐analysis of five studies reveals higher complete biochemical response rates, increased Corticosteroid withdrawal rate, and fewer gastrointestinal side effects with MMF.
Muhammad Tayyab Anwar, Muhammad Shahzil, Taha Bin Arif, Muhammad Ali Khaqan, Edzel Lorraine Co, Fariha Hasan, Rameez Tarar, Hamza Naeem, Sibgha Farooq, Ali Jaan, Ammad Javaid Chaudhary, Vinay Jahagirdar, Reena Salgia   +12 more
wiley   +1 more source

Prevalence and incidence of comorbidities in patients with atopic dermatitis, psoriasis, alopecia areata, and vitiligo using a Japanese claims database. [PDF]

J Dermatol
Ma Y, Chachin M, Hirose T, Nakamura K, Shi N, Hiro S, Imafuku S.   +6 more
europepmc   +1 more source

SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation

Aging Cell, EarlyView.
p62 exhibits diminished expression in aging skin and senescent cells. p62 serves to inhibit the accumulation of USP7 during senescence induction. The Tyr‐67 residue within the PB1 domain or Gln‐418 within the UBA domain of p62 forms a hydrogen bond with Ala‐993 of the Ubl5 domain of USP7.
Liu Chen, Xiaoping Wang, Yuchen Wang, Qingxin Yao, Yunyao Liu, Yongcheng Zhu, He Huang, Hedan Yang, Yin Yang, Yuan He, Lei Qiang   +10 more
wiley   +1 more source

Analyzing Social Media Trends in Cosmeceuticals: Insights From Google Trends and TikTok Analytics. [PDF]

J Cosmet Dermatol
Correia E, Mandel J, Cullison SRJ.
europepmc   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott, Videha Sharma, Jessica Keen, William Gerard Newman   +3 more
wiley   +1 more source

The Impact of Surgery on Quality of Life in Hidradenitis Suppurativa: Results from a Prospective Single-Center Study. [PDF]

Life (Basel)
Ocker L, Abu Rached N, Koller A, Frost C, Käpynen R, Bechara FG.   +5 more
europepmc   +1 more source