Results 281 to 290 of about 3,310,854 (363)

Eight‐Year Experience of Hedgehog Pathway Inhibitors at Three Tertiary Referral Centres in the Australian State of Victoria

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT This retrospective analysis of Hedgehog inhibitor treatment in 32 patients with Gorlin syndrome, locally advanced and metastatic basal cell carcinoma (BCC) at three tertiary referral centres in Victoria, Australia from April 2017 until 30 June 2024 demonstrated an 84% overall objective response rate (partial and complete response combined ...
Christian Gan   +4 more
wiley   +1 more source

Psychosocial Determinants and Atopic Dermatitis Outcomes: A Cross‐Sectional Study From an Australian Paediatric Centre

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) significantly impacts quality of life, with well‐documented physical and psychological consequences. While disease burden is well characterised, the influence of psychosocial determinants on AD outcomes remains underexplored. This study examines these factors in an Australian paediatric population.
Ashling Courtney   +5 more
wiley   +1 more source

CT‐P39 Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double‐Blind, Randomized, Active‐Controlled, Phase 3 Study

open access: yesAllergy, EarlyView.
This study investigated the therapeutic equivalence of CT‐P39 (an omalizumab biosimilar) and EU‐approved reference omalizumab (ref‐OMA) in patients with chronic spontaneous urticaria. Therapeutic equivalence between CT‐P39 and ref‑OMA (300 mg) was demonstrated by the primary endpoint – confidence intervals of the treatment difference in mean change ...
Sarbjit S. Saini   +16 more
wiley   +1 more source

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

open access: yesAllergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka   +28 more
wiley   +1 more source

Enteropathic SAPHO Syndrome in Ulcerative Colitis Responsive to Bisphosphonates. [PDF]

open access: yesCase Rep Rheumatol
Phillipps J   +6 more
europepmc   +1 more source

Economic Impact of Allergic Diseases and Asthma—The HEAD Pan‐European Registry

open access: yesAllergy, EarlyView.
This registry‐based study demonstrates the substantial economic burden of allergic diseases across Europe with a high degree of heterogeneity between countries. Treatments and specialist visits are the primary drivers of healthcare costs. Asthma poses the highest disease burden.
Ioana Agache   +66 more
wiley   +1 more source

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