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Understanding Toxicities of Targeted Agents: Implications for Anti-tumor Activity and Management.

Seminars in Oncology, 2015
Targeted treatments have distinctive side effects: dermatologic problems (rash, hand-food skin reaction, skin/hair whitening), endocrine dysfunction (hyperglycemia, hypothyroidism, dyslipidemia), as well as hypertension, diarrhea, liver problems, ocular ...
Sariah Liu, R. Kurzrock
semanticscholar   +1 more source

Keratinolytic Agents in Dermatology

1990
Keratin is an essential constituent of the keratin laminae which, together with the intercellular substances in the skin, form the stratum corneum with its barrier function and give the hair and nails their physical properties.
openaire   +2 more sources

Biological Agents in Pediatric Dermatology

2017
Biological agents are revolutionizing the treatment of immune-mediated disease across many disciplines, including rheumatology, gastroenterology, and dermatology. For children with psoriasis, these medications represent a welcome alternative to broad immunosuppressants such as methotrexate and cyclosporine when topical therapies are inadequate.
Emily B. Lund, Amy S. Paller
openaire   +2 more sources

Targeted Agents: Management of Dermatologic Toxicities [PDF]

open access: possibleJournal of the National Comprehensive Cancer Network, 2014
Epidermal growth factor receptor (EGFR) inhibitors are widely used in the treatment of many cancers, and the cutaneous toxicity profile associated with these agents has become prominent. In fact, dermatologic side effects have also been reported with other targeted agents, including both BRAF and mTOR inhibitors.
openaire   +2 more sources

The Use and Abuse of Immunosuppressive Agents in Dermatology

Archives of Dermatology, 1985
In this issue of theArchives, Paslin 1 describes three patients in whom a remission of lichen planus occurred as a consequence of short-term cyclophosphamide therapy. It was obviously a small, open-label drug trial, and therefore, it should be interpreted carefully.
Ira Bell, Gerald D. Weinstein
openaire   +3 more sources

New Dermatological Agents for the Treatment of Psoriasis

Journal of Medicinal Chemistry, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Roshantha A.S. Chandraratna   +4 more
openaire   +4 more sources

Cytotoxic agents for use in dermatology. I

Journal of the American Academy of Dermatology, 1985
There are indications for the use of cytotoxic drugs in some dermatologic diseases. These drugs may be lifesaving for patients with diseases such as pemphigus, lymphomas, and vasculitis or they may merely offer an improved quality of life for patients who have diseases such as psoriasis, progressive systemic sclerosis, or sarcoidosis.
openaire   +3 more sources

Overview of biologic agents in medicine and dermatology

Seminars in Cutaneous Medicine and Surgery, 2005
Three agents have recently been approved by the Food and Drug Administration for the treatment of chronic plaque psoriasis: alefacept, efalizumab, and etanercept. The field of dermatology has now entered a new era, joining other disciplines of medicine that have been using biologic agents for decades.
openaire   +3 more sources

New Therapeutic Agents in Veterinary Dermatology

Veterinary Clinics of North America: Small Animal Practice, 1990
The rapid development of therapeutic agents will continue to provide veterinarians with new options in treating dermatologic disease. However, we must not overlook the possibility of new applications for older drugs. Ideally, before a drug can be recommended for routine use, it should be evaluated for safety and efficacy using unbiased scientific ...
openaire   +3 more sources

Management of antithrombotic agents in dermatologic surgery before and after publication of the corresponding German evidence‐based guideline

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018
M. Gaskins   +6 more
semanticscholar   +1 more source

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