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Understanding Toxicities of Targeted Agents: Implications for Anti-tumor Activity and Management.
Seminars in Oncology, 2015Targeted treatments have distinctive side effects: dermatologic problems (rash, hand-food skin reaction, skin/hair whitening), endocrine dysfunction (hyperglycemia, hypothyroidism, dyslipidemia), as well as hypertension, diarrhea, liver problems, ocular ...
Sariah Liu, R. Kurzrock
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Keratinolytic Agents in Dermatology
1990Keratin is an essential constituent of the keratin laminae which, together with the intercellular substances in the skin, form the stratum corneum with its barrier function and give the hair and nails their physical properties.
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Biological Agents in Pediatric Dermatology
2017Biological agents are revolutionizing the treatment of immune-mediated disease across many disciplines, including rheumatology, gastroenterology, and dermatology. For children with psoriasis, these medications represent a welcome alternative to broad immunosuppressants such as methotrexate and cyclosporine when topical therapies are inadequate.
Emily B. Lund, Amy S. Paller
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Targeted Agents: Management of Dermatologic Toxicities [PDF]
Epidermal growth factor receptor (EGFR) inhibitors are widely used in the treatment of many cancers, and the cutaneous toxicity profile associated with these agents has become prominent. In fact, dermatologic side effects have also been reported with other targeted agents, including both BRAF and mTOR inhibitors.
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The Use and Abuse of Immunosuppressive Agents in Dermatology
Archives of Dermatology, 1985In this issue of theArchives, Paslin 1 describes three patients in whom a remission of lichen planus occurred as a consequence of short-term cyclophosphamide therapy. It was obviously a small, open-label drug trial, and therefore, it should be interpreted carefully.
Ira Bell, Gerald D. Weinstein
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New Dermatological Agents for the Treatment of Psoriasis
Journal of Medicinal Chemistry, 2001AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Roshantha A.S. Chandraratna+4 more
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Cytotoxic agents for use in dermatology. I
Journal of the American Academy of Dermatology, 1985There are indications for the use of cytotoxic drugs in some dermatologic diseases. These drugs may be lifesaving for patients with diseases such as pemphigus, lymphomas, and vasculitis or they may merely offer an improved quality of life for patients who have diseases such as psoriasis, progressive systemic sclerosis, or sarcoidosis.
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Overview of biologic agents in medicine and dermatology
Seminars in Cutaneous Medicine and Surgery, 2005Three agents have recently been approved by the Food and Drug Administration for the treatment of chronic plaque psoriasis: alefacept, efalizumab, and etanercept. The field of dermatology has now entered a new era, joining other disciplines of medicine that have been using biologic agents for decades.
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New Therapeutic Agents in Veterinary Dermatology
Veterinary Clinics of North America: Small Animal Practice, 1990The rapid development of therapeutic agents will continue to provide veterinarians with new options in treating dermatologic disease. However, we must not overlook the possibility of new applications for older drugs. Ideally, before a drug can be recommended for routine use, it should be evaluated for safety and efficacy using unbiased scientific ...
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Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018
M. Gaskins+6 more
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M. Gaskins+6 more
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