Results 141 to 150 of about 16,089,508 (287)

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

СРАВНИТЕЛЬНАЯ ОЦЕНКА DERMATOLOGY LIFE QUALITY INDEX У БОЛЬНЫХ ПСОРИАЗОМ И ПСОРИАТИЧЕСКИМ АРТРИТОМ

, 2020
The article "Comparative evaluation of the Dermatology Life Quality Index in patients with psoriasis and psoriatic arthritis" is devoted to the analysis of problems of psoriasis. The author shows that dermatological diseases and comorbid pathology have a
Malyarenko E.N., Gitinova M.M., Batkaev E.A., Batkaeva N.V.   +3 more
core  

Medición de la calidad de vida por medio del Dermatology Life Quality Index en pacientes con psoriasis: una revisión sistemática [PDF]

, 2013
Objective: To evaluate quality of life related to health in patients with psoriasis, through the Dermatology Life Quality Index (DLQI).Methods: A systematic review about quality of life related to health in patients with psoriasis and has been ...
Londoño, Ángela, Jiménez, Sol, Ordóñez, Jaime, Palacios, Árlex   +3 more
core  

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling, Ravish N. Gangapersad, Lillian Lieuw, Patrick C. Souverein, Eibert R. Heerdink, Pilar Garcia‐Gomez, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx   +8 more
wiley   +1 more source

Quality of life in children with psoriasis: results from a monocentric study

, 2019
BACKGROUND: Psoriasis is a chronic inflammatory disease that can impair quality of life and psychological status not only in adult patients, but also in children. Few data about quality of life in children with psoriasis are available in literature.
Nobile, Francesca, Milazzo, Eleonora, Ventura, Laura, Marogna, Cristina, Zacchino, Matteo, Caroppo, Francesca, Fontana, Elena, Belloni Fortina, Anna, Zacchino M., Caroppo F., Ventura L., Nobile F., Fontana E., Belloni Fortina A., Milazzo E., Marogna C., Elena FONTANA, Anna BELLONI FORTINA, Matteo ZACCHINO, Eleonora MILAZZO, Francesca CAROPPO, Laura VENTURA, Francesca NOBILE, Cristina MAROGNA   +23 more
core   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

Decision for biological treatment in real life is more strongly associated with the Psoriasis Area and Severity Index (PASI) than with the Dermatology Life Quality Index (DLQI)

, 2015
BACKGROUND: Following the establishment of the National Quality Registry for systemic psoriasis treatment (PsoReg), the two psoriasis outcome measurements, Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI), are now ...
Eriksson, Marie,, Hägg, David,, Sundström, A, Schmitt-Egenolf, Marcus,   +3 more
core   +1 more source

Phase 1, open‐label, randomized study of the elecoglipron pharmacokinetic profile in healthy participants under fed and fasted conditions

British Journal of Clinical Pharmacology, EarlyView.
Aims Elecoglipron (AZD5004/ECC5004) is an oral small‐molecule glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) in development for weight management in people living with obesity or overweight and type 2 diabetes. This study aimed to characterize the pharmacokinetics (PK) profiles of two formulations of elecoglipron under fed and fasted conditions ...
Jianfeng Xu, Amina Haggag, Laurie Butcher, Haihui Liu, Wen Chen, Xuefeng Sun, Aruni Jha, Hongtao Yu, Anis Khan, Victoria E. R. Parker, Christer Tannergren, Xiaoliang Pan, Jianfeng Xu, Jingye Zhou   +13 more
wiley   +1 more source

Correlation between Dermatology Life Quality Index and Minor Test and Differences in Their Levels over Time in Patients with Axillary Hyperhidrosis Treated with Botulinum Toxin Type A

, 2011
Hyperhidrosis is an idiopathic condition of exaggerated sweat production resulting in dramatic impairments of daily activities, social interactions and occupational activities. The aim of the present study was to evaluate correlation between a subjective
LA TORRE, Giuseppe, LA VIOLA, GIORGIO, SKROZA, Nevena, BERNARDINI, NICOLETTA, POTENZA, Concetta   +4 more
core  

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source