Results 211 to 220 of about 59,004 (282)

Successful Rescue Therapy With Daratumumab in Rapidly Progressive Interstitial Lung Disease Caused by MDA5-Positive Dermatomyositis.

Chest, 2023
Melanoma differentiation-associated gene 5 (MDA5) positive dermatomyositis is a rare systemic autoimmune disease that is associated with life-threatening rapidly progressive interstitial lung disease. We report the case of a 19-year-old male patient with
M. Holzer, Jasper F. Nies, T. Oqueka, T. Huber, I. Kötter, M. Krusche   +5 more
semanticscholar   +1 more source

Anti-SAE autoantibody in dermatomyositis: original comparative study and review of the literature.

Rheumatology, 2023
OBJECTIVE Among specific autoantibodies in dermatomyositis, the anti-SAE antibody is rare. We aim to describe clinical characteristics, cancer prevalence, and muscle pathology of anti-SAE positive dermatomyositis.
Juliette Demortier, M. Vautier, O. Chosidow, L. Gallay, D. Bessis, A. Bérézné, N. Cordel, J. Schmidt, A. Smail, P. Duffau, M. Jachiet, E. Bégon, J. Gottlieb, F. Chasset, J. Graveleau, M. Marque, E. Cesbron, A. Forestier, S. Josse, N. Kluger, Caroline Beauchene, Y. Le Corre, V. Pagis, A. Rigolet, P. Guillaume-Jugnot, F. Authier, Nelly Guilain, N. Streichenberger, S. Leonard-Louis, S. Boussouar, O. Landon-Cardinal, O. Benveniste, Y. Allenbach   +32 more
semanticscholar   +1 more source

Management of MDA-5 antibody positive clinically amyopathic dermatomyositis associated interstitial lung disease: A systematic review.

Seminars in Arthritis & Rheumatism, 2022
INTRODUCTION Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive clinically amyopathic dermatomyositis (CADM) is frequently associated with rapidly progressive interstitial lung disease (RP-ILD) and high mortality rates.
M. McPherson, Sofia C Economidou, A. Liampas, P. Zis, K. Parperis   +4 more
semanticscholar   +1 more source

Identification of Three Different Phenotypes in Anti–Melanoma Differentiation–Associated Gene 5 Antibody–Positive Dermatomyositis Patients: Implications for Prediction of Rapidly Progressive Interstitial Lung Disease

Arthritis & Rheumatology, 2022
There is substantial heterogeneity among the phenotypes of patients with anti–melanoma differentiation–associated gene 5 antibody–positive (anti‐MDA5+) dermatomyositis (DM), hindering disease assessment and management.
Lingxiao Xu, H. You, Lei Wang, C. Lv, F. Yuan, Ju Li, Min Wu, Z. Da, Hua Wei, Weiping Yan, Lei Zhou, Songlou Yin, Dongmei Zhou, Jian Wu, Yan Lu, D. Su, Zhichun Liu, Lin Liu, Longxin Ma, Xiaoya Xu, Y. Zang, Huijie Liu, Tianli Ren, Fang Wang, Yan Du, Jing Xue, Miaojia Zhang, W. Tan   +27 more
semanticscholar   +1 more source

Dermatomyositis Part I: Clinical Features and Pathogenesis.

Journal of American Academy of Dermatology, 2020
Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically heterogeneous and can be difficult to diagnose. Cutaneous manifestations sometimes vary and may or may not parallel myositis and systemic involvement in time course and/or ...
M. DeWane, R. Waldman, Jun Lu
semanticscholar   +1 more source

Anti-MDA5 dermatomyositis: an update from bench to bedside

Current Opinion in Rheumatology, 2022
Purpose of review This review summarizes the recent developments about anti-MDA5 antibody positive dermatomyositis with a focus on its pathogenesis, clinical features and treatment options of rapidly progressive interstitial lung disease, its most ...
Enrico Fuzzi, M. Gatto, M. Zen, C. Franco, E. Zanatta, A. Ghirardello, A. Doria   +6 more
semanticscholar   +1 more source

Dermatomyositis und juvenile Dermatomyositis

Zeitschrift für Rheumatologie, 2022
Dermatomyositis (DM) is an inflammatory multisystem disease of unknown etiology, which can already occur in children but first onset can also be in older adulthood. Myalgia and muscle weakness can occur later in the course of the disease or even be completely absent in some forms.
Frank, Dressler, Britta, Maurer
openaire   +2 more sources

Characteristics of dermatomyositis patients with and without associated malignancy

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2021
Dermatomyositis belongs to the rare idiopathic, inflammatory myositis group. A previously postulated link between some cases of dermatomyositis and malignancy has been established in recent years. Criteria suggestive of a malignancy association are still
J. Lauinger, K. Ghoreschi, S. Volc
semanticscholar   +1 more source

Dermatomyositis

Journal of the American Academy of Dermatology, 1998
Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and muscular weakness. The disease can be categorized as adult idiopathic, juvenile, or amyopathic dermatomyositis as well as that associated with a connective tissue disease or a malignancy.
S O, Kovacs, S C, Kovacs
openaire   +2 more sources

Dermatomyositis: Diagnosis and treatment

Journal of American Academy of Dermatology, 2020
The second article in this continuing medical education series reviews the initial evaluation of patients with suspected dermatomyositis (DM), the relevant work-up for malignancy and interstitial lung disease once a diagnosis of DM is made, and treatment
R. Waldman, M. DeWane, Jun Lu
semanticscholar   +1 more source