Results 81 to 90 of about 49,613 (221)

Serum KL‐6 level is a prognostic marker in patients with anti‐MDA5 antibody‐positive dermatomyositis associated with interstitial lung disease

open access: yesJournal of clinical laboratory analysis (Print), 2019
This study aimed to investigate the clinical significance of Krebs von den Lungen‐6 (KL‐6) serum levels in patients with anti‐MDA5 antibody‐positive dermatomyositis (anti‐MDA5+ DM) having interstitial lung disease (ILD), especially in the amyopathic DM ...
Y. Ye   +4 more
semanticscholar   +1 more source

The Five‐Day Trajectory of Nutritional Indicators and Influencing Factors in Adult Patients After VA‐ECMO: A Prospective Observational Study

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Objective This study aimed to characterize the 5‐day trajectory of nutritional and metabolic profiles and identify influencing factors in adults receiving VA‐ECMO support. Methods A total of 46 patients with cardiogenic shock receiving VA‐ECMO (2022–2024; median age 50 [IQR: 41.0–63.3]) were prospectively enrolled.
Wenyu Li   +6 more
wiley   +1 more source

Tacrolimus Trough Concentration‐Escalating Bipartite Therapy (Glucocorticoids Combined With Tacrolimus) for Refractory MDA5 Antibody‐Positive Clinically Amyopathic Dermatomyositis With Rapidly Progressive Interstitial Pneumonia

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.
ABSTRACT Objective This study aimed to determine the outcomes of patients that have refractory anti‐melanoma differentiation‐associated gene 5 (MDA5) antibody‐positive clinically amyopathic dermatomyositis with rapidly progressive interstitial pneumonia treated with tacrolimus trough concentration‐escalating bipartite therapy (glucocorticoids combined ...
Anji Xiong   +10 more
wiley   +1 more source

Skeletal Muscle Membrane Permeability Markers Derived From 31P‐MRS May Reflect Disease Activity in Becker Muscular Dystrophy

open access: yesNMR in Biomedicine, Volume 38, Issue 11, November 2025.
Biomarkers for muscle disease activity are needed for trials in Becker muscular dystrophy (BMD). We investigated magnesium (Mg2+), phosphodiesters (PDE) and pH from 31P‐MRS; and membrane permeability from random permeable barrier model (RBPM) diffusion as candidates, studying ‘preserved’ and ‘progressing’ muscles in patients with BMD versus controls ...
Esther J. Schrama   +5 more
wiley   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

open access: yesActa Paediatrica, Volume 114, Issue 11, Page 2993-2999, November 2025.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä   +2 more
wiley   +1 more source

Dermatomyositis presenting with symptomatic dermographism and raised troponin T: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Dermatomyositis is an important inflammation of skin and muscles. Generalised itch is frequent in the condition; however, symptomatic dermographism has not previously been reported as a presenting feature.
Rahim Kartini F, Dawe Robert S
doaj   +1 more source

Itch in dermatomyositis: the role of increased skin interleukin‐31

open access: yesBritish Journal of Dermatology, 2018
Interleukin (IL)‐31 is implicated in pruritus associated with pruritic skin diseases like atopic dermatitis. Although pruritus is a prominent feature in dermatomyositis (DM), few studies have evaluated the pathogenesis of DM‐associated itch.
H. J. Kim   +6 more
semanticscholar   +1 more source

The Role of C/EBP‐Homologous Protein in Idiopathic Inflammatory Myopathies

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT The Idiopathic Inflammatory Myopathies (IIMs) are a group of autoimmune disorders characterised by persistent muscle inflammation and diverse clinical manifestations. Common symptoms include muscle weakness, myalgia, and elevated serum creatine kinase levels. Recent findings highlight the relevance of muscle fibre necrosis in IIMs.
Monica Sciacco   +9 more
wiley   +1 more source

FRI0470 A phase 2 study of safety and efficacy of lenabasum (JBT-101), a cannabinoid receptor type 2 agonist, in refractory skin-predominant dermatomyositis [PDF]

open access: bronze, 2018
Victoria P. Werth   +11 more
openalex   +1 more source

Concern about malignancy contributes to the psychosocial toll of dermatomyositis

open access: green, 2021
MF Helm   +5 more
openalex   +2 more sources

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