Results 121 to 130 of about 36,760 (309)

Tildrakizumab in real-world Chinese psoriasis: efficacy-safety profiles from a 28-week retrospective cohort with geriatric, late-onset and metabolic syndrome stratification

Journal of Dermatological Treatment
Objective To assess the real-world efficacy and safety of tildrakizumab in Chinese patients with psoriasis stratified by age, age of psoriasis onset and MetS status.Methods This two-center retrospective cohort study evaluated tildrakizumab’s efficacy and
Qianzi Liu, Kun Hu, Yang Sha, Chengzhi Lv, Yehong Kuang   +4 more
doaj   +1 more source

A Verrucous Plaque After Traumatic Inoculation

JEADV Clinical Practice, EarlyView.
Juan Felipe Ochoa‐Bermudez, Paula Andrea Hernández‐Arias, Maria Valentina Oliver‐Hernández, Samuel Morales, ÁlvaroTovar Cock   +4 more
wiley   +1 more source

External Genital Cutaneous Sarcoidosis Mimicking Lichen Sclerosus

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Although external genital cutaneous sarcoidosis is rare, it can closely resemble lichen sclerosus (LS) and delay diagnosis. We report a case of a 69‐year‐old woman with long‐standing vulvar symptoms and LS‐like pallor of the labia minora and clitoris. Biopsy showed non‐caseating granulomas with negative infection stains, consistent with vulvar
Enakshi Mudalige, Annabel Stevenson
wiley   +1 more source

An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI Activation

Allergy, EarlyView.
FcεRI cross‐linking triggers widespread transcriptional reprogramming in human skin mast cells (> 5000 genes, > 6400 promoters, and 48 novel mast cell‐enriched lncRNAs). Breast skin and foreskin mast cells share core transcriptional programs but differ selectively in tryptase isoenzymes and IL‐8/IL‐1RA release.
Gürkan Bal, Kristin Franke, Stefan Frischbutter, Shiva Raj Tripathi, Kayoko Yasuzawa, Jordan A. Ramilowski, Michihira Tagami, Takeya Kasukawa, Michiel de Hoon, Jay W. Shin, Piero Carninci, Torsten Zuberbier, Magda Babina   +12 more
wiley   +1 more source

Ashy Dermatosis - Treatment with Clofazimine [PDF]

, 2012
A Ashy dermatosis, ou erythema dyscromicum perstans, é uma dermatose rara de etiologia desconhecida. Os autores descrevem o caso de um homem de 46 anos saudável, com história de lesões cutâneas cinzentas assintomáticas no tronco com 1 ano de evolução ...
Caetano, M., Alves, R., Selores, M., Pinto-Almeida, T.   +3 more
core  

The PENIMA project: artificial intelligence decision‐support tool for penile lesions – protocol paper and invitation to participate

BJU International, EarlyView.
Objectives To present and describe the design, data collection framework, and interim cohort characteristics of the PENIMA project, a multicentre initiative establishing a clinically annotated penile lesion image repository to support future artificial intelligence (AI)‐driven decision‐support development – and to encourage urology and dermatology ...
Janni Mølsted, Anne Birgitte Als, Jørgen Bjerggaard Jensen, Mikael Aagaard, Lisa Anni Larsen Lethan, Sinja Kristiansen, Christian Arvei Moen, Axel Gerdtsson, Line Kibsgaard, Christina Gade Jespersen, Frederikke Eichner Sørensen, Ann‐Kathrine Rossau, Jens Kramer Rangen, Jakob Kristian Jakobsen   +13 more
wiley   +1 more source

Peeling paint dermatosis

The Pan African Medical Journal
A 4-month-old infant presented with complaints of inability to take feeds, peeling skin all over the body, with a history of loose stools two weeks back. There was no significant past or birth history. On examination, the infant was irritable, with generalized oedema present, dehydrated, weight for height in 62nd percentile, pulse rate 130 beats ...
openaire   +3 more sources

Fibrillar‐Type Dermatitis Herpetiformis: An Underrecognized Variant That Is Rarely Associated With Celiac Disease and Lacking Epidermal Transglutaminase Deposition: A Report of Two Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman, Elodie Mendels, Sven van der Woude, Sharon Veenbergen, Gilles F. H. Diercks, Martijn B. van Doorn   +5 more
wiley   +1 more source

Utility of IL‐18 Immunohistochemistry in Distinguishing Dermatomyositis and Lupus Erythematosus in Skin Biopsies

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinction of dermatomyositis (DM) and cutaneous lupus erythematosus (LE) in skin biopsies is often difficult due to significant histopathologic overlap. Prior transcriptional analysis has identified upregulation of IL‐18 in DM compared with LE.
Steven M. Hrycaj, Joseph S. Durgin, Johann E. Gudjonsson, J. Michelle Kahlenberg, Gaidaa R. Majari, Carole Bitar, Catherine G. Chung, Rosalynn M. Nazarian, May P. Chan   +8 more
wiley   +1 more source

Novel ribosome biogenesis-related biomarkers and therapeutic targets identified in psoriasis

Scientific Reports
Psoriasis is an immune-mediated chronic inflammatory disease. Increasing evidence suggests a close association between ribosome biogenesis (RiboSis) and the pathogenesis of psoriasis. However, the precise mechanisms remain unclear. We first obtained bulk
Jinghua Liu, Nana Luo, Wenyi Ma, Zeyun Qiao, Xiaojing Zhong, Zilin Cheng, Pingsheng Hao, Chengzhi lv   +7 more
doaj   +1 more source