Results 81 to 90 of about 36,760 (309)

Demographic and laboratory characteristics of neurosyphilis: a retrospective cohort study from a tertiary dermatosis hospital

BMC Infectious Diseases
Background Neurosyphilis, a severe manifestation of syphilis caused by Treponema pallidum invasion into the central nervous system, exhibits diverse clinical subtypes.
Yun He, Ai-Hong Gong, Hui-lin Zhang, Yu-Yan Chen, Xiao-Liang Liang, Bing-Lei Li, Lian-Jiang Huang, Cheng-Zhi Lv, Ai-Li Li   +8 more
doaj   +1 more source

Erythema dyschromicum perstans (ashy dermatosis) – opis przypadków

, 2011
Introduction. Erythema dyschromicum perstans (EDP) is an acquireddisease, rare in the Caucasian race, with characteristic greyish, ashycolouredskin lesions. The aetiology of the disease is unknown.Objective.
Magdalena Trzeciak, Jadwiga Roszkiewicz, Małgorzata Sokołowska-Wojdyło, Magdalena Lange   +3 more
core  

The Physician Global Assessment as a Proxy for Photoaging: Validation in an Observational Real‐World Cohort Using SCINEXA as the Reference Standard

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Photoaging is a chronic skin condition caused by cumulative ultraviolet exposure superimposed on intrinsic aging. Although the SCore of INtrinsic and EXtrinsic skin Aging (SCINEXA) is a validated multidimensional instrument for assessing photoaging, the Physician Global Assessment (PGA) is a simpler clinician‐reported measure whose ...
Ewout Baerveldt, Eric van Sprang, Henk‐Jan Ramaker, Robert T. Aeneae Venema, Thomas Rustemeyer, Jorrit Terra, Perry J. J. van Genderen   +6 more
wiley   +1 more source

DeepCas12a: a hybrid deep learning framework for accurate AsCas12a efficiency prediction from sequence and epigenetic information

BMC Genomics
CRISPR-Cas12a (Cpf1) offers distinct advantages for genome editing due to its flexible, T-rich PAM recognition. However, variable cleavage efficiency—modulated by sequence context and epigenetic features—remains a challenge, with existing tools facing ...
Yiming Shi, Junkai Yin, Shurui Ning, Jinling Yuan, Degang Yang, Guohui Chuai   +5 more
doaj   +1 more source

The regulatory mechanisms and treatment of HDAC6 in immune dysregulation diseases

Frontiers in Immunology
Histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that contains two catalytic domains and a zinc finger ubiquitin binding domain (ZnF-UBP). The deacetylation function of HDAC6 has been extensively studied with well-characterized substrates
Yanyang Liang, Yanyang Liang, Ying Wang, Ying Wang, Jianxiao Xing, Jianxiao Xing, Junqin Li, Junqin Li, Kaiming Zhang, Kaiming Zhang   +9 more
doaj   +1 more source

Redefining Acne as a Distinct Inflammatory Disease: Acne Is Not an Aesthetic Issue

JEADV Clinical Practice, EarlyView.
Jean Paul Claudel, Fabienne Ballanger, Nicole Auffret, Marie‐Thérèse Leccia, Brigitte Dréno   +4 more
wiley   +1 more source

Line‐Field Confocal Optical Coherence Tomography: A Diagnostic Tool Facilitating the Diagnosis of Sweet's Syndrome. A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Sweet's syndrome is a rare neutrophilic dermatosis characterized by an acute onset of erythematous and infiltrative lesions. Diagnosis is based on clinical, histopathological, and laboratory findings. We propose that non‐invasive skin imaging techniques, such as line‐field confocal optical coherence tomography (LC‐OCT), may be beneficial for ...
Aleksandra Anderson, Piotr Konopelski, Mariano Suppa, Joanna Czuwara, Marta Kurzeja, Lidia Rudnicka   +5 more
wiley   +1 more source

Retrospective analysis of non-tuberculous mycobacterial skin infections: diagnostic accuracy, treatment efficacy, and PCR-based species detection in a Chinese primary care hospital

Journal of Clinical Microbiology
Non-tuberculous mycobacterial (NTM) skin infections present diagnostic and therapeutic challenges in resource-limited primary care settings. This retrospective study evaluated the diagnosis and treatment of NTM skin infections at a primary care hospital ...
Tianyi Xu, Yingjie Zheng, Ruoning Xue, Ruoyu Li, Wen Zhang, Zaihong Sun, Yinggai Song   +6 more
doaj   +1 more source

Dermatosis por virus

, 2020
Temario oficial de la asignatura de Dermatología de la Titulación de Grado en Medicina de la Universidad de Cádiz. Tema 14.
Armario Hita, José Carlos
core  

The Inverse Koebner Phenomenon in Cutaneous T‐Cell Lymphomas

JEADV Clinical Practice, EarlyView.
Alba Guglielmo, Corrado Zengarini, Alessandro Borghi, Alessandro Pileri   +3 more
wiley   +1 more source