ABSTRACT The Flexible and Interactive Tradeoff Elicitation (FITradeoff) method is a Multi‐Attribute Decision‐Making (MADM) approach designed to capture the preferences of a Decision Maker (DM) while minimising cognitive effort. To reduce the frequency of interactions and optimise the preference elicitation process, this paper introduces an innovative ...
Qian Zhao +3 more
wiley +1 more source
Tell Me How Much DNA You Have and I'll Tell You What Your Sex Is: Sex Determination by Flow Cytometry of Spiderlings of <i>Allocosa marindia</i>. [PDF]
Bidegaray-Batista L +4 more
europepmc +1 more source
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova +5 more
wiley +1 more source
Comparative analysis of anti-MICA scFv affinities: Insights from three label-free biophysical methods and biological validation. [PDF]
Toledo-Stuardo K +22 more
europepmc +1 more source
ABSTRACT Aim Human monocarboxylate transporters 1–4, MCT, are key for the lactate/H+ exchange between glycolytic and oxidative cancer cells, white and red muscle fibers, or in the astrocyte‐neuron shuttle. The common MCT transport mechanism involves three conserved residues, that is, a substrate‐attracting Lys and a conformation‐locking Asp/Arg salt ...
Maike Menzel +6 more
wiley +1 more source
Adsorption Characteristics and Mechanistic Role of Ionic Species on the Chalcopyrite (112) Surface Based on DFT Simulations. [PDF]
Rios-Colque L +3 more
europepmc +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Early fault detection in gearboxes via dynamic principal component analysis-driven multivariate statistical process control. [PDF]
Pérez-Torres A +4 more
europepmc +1 more source
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
Guava Byproducts (<i>Psidium guajava</i> L.) as a Source of Phenolic Compounds with In Vitro Antihyperlipidemic Potential. [PDF]
Baeza-Jiménez R +4 more
europepmc +1 more source

