Results 161 to 170 of about 23,348 (213)

The Activation of Aldehyde Dehydrogenase 2 (ALDH2) by Alda-1 and Flurbiprofen as a Common Mechanism to Reduce Alcohol Intake in Rats. [PDF]

open access: yesInt J Mol Sci
Torres JM   +6 more
europepmc   +1 more source

Risk management strategies in higher education

open access: yesEuropean Management Review, EarlyView.
Abstract Higher education centres are facing escalating risks, such as increasing competition from a growing number of higher education organisations, as well as greater exposure to more complex regulatory frameworks and external evaluations. Consequently, university risk management has assumed increasing significance.
Washington Guevara‐Piedra   +2 more
wiley   +1 more source

[Long-term outcomes of maxillectomy for paranasal sinus cancer]. [PDF]

open access: yesRev Med Inst Mex Seguro Soc
Ramírez-Echavarría A   +4 more
europepmc   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Colourful agrobiodiversity: morphology and phenology of bean landraces to face commodification of the commons in the southern Andes. [PDF]

open access: yesBot Stud
Romero-Silva MJ   +4 more
europepmc   +1 more source

Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1

open access: yesThe FEBS Journal, EarlyView.
In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández   +4 more
wiley   +1 more source

Implementation of an Intervention Program Based on Virtual Walking and Therapeutic Exercise in Cuba: A Feasibility Study. [PDF]

open access: yesHealthcare (Basel)
Moreno-Segura N   +4 more
europepmc   +1 more source

Recompression Improves Release Success in Pollack (Pollachius pollachius): A Step Towards Assessing Post Release Mortality in a Recreational Fishery

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT The recreational fishery for pollack (Pollachius pollachius) in the northeast Atlantic is impacted by the species' high sensitivity to barotrauma. When captured at depth and brought to the surface, gas expansion within the peritoneal cavity can cause a variety of injuries and hinder release.
T. Stamp   +15 more
wiley   +1 more source

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