Results 291 to 300 of about 2,942,312 (345)

Efficacy of NAMPT Inhibitors in Pancreatic Cancer After Stratification by MAP17 (PDZK1IP1) Levels. [PDF]

Cancers (Basel)
Verdugo-Sivianes EM, Martínez-Pérez J, Navas LE, Sáez C, Carnero A.   +4 more
europepmc   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

The FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova, Anna N. Khusnutdinova, Hairong Ma, Manuel Ferrer, Olga V. Golyshina, Alexander F. Yakunin, Peter N. Golyshin   +6 more
wiley   +1 more source

CPAP improves regional lung strain rate and diaphragm velocity of relaxation in experimental self-inflicted lung injury. [PDF]

Crit Care
Pérez A, Erranz B, Reveco S, González C, Avilés-Rojas N, Hurtado DE, Cruces P.   +6 more
europepmc   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

[Substandard and falsified medical products: 25 years of successful network collaboration among regulatory authorities in the AmericasProdutos médicos de qualidade inferior e falsificados: 25 anos de colaboração bem-sucedida em rede entre autoridades reguladoras da Região das Américas]. [PDF]

Rev Panam Salud Publica
Vahos Zambrano J, Carrasco G, Rojas-Cortés R, Alfonso MJ, Viñas R, Derecho M, Munguía M, Marin D, Castro JL, Pombo-Castro ML.   +9 more
europepmc   +1 more source

Effects of the Center-Edge Gradient and Habitat Type on the Spatial Distribution of Plant Species Richness in Santiago, Chile. [PDF]

Plants (Basel)
Castro SA, Ray C, Figueroa JA, Alfaro M, Orrego F, Vergara PM.   +5 more
europepmc   +1 more source

[Risk of transfusion and transplantation transmission of <i>Trypanosoma cruzi</i> infection in endemic countries in the AmericasRisco de infecção por <i>Trypanosoma cruzi</i> por transfusão e transplante em países endêmicos da Região das Américas]. [PDF]

Rev Panam Salud Publica
Beltrán M, Remesar M, Menjivar A, Barco G.   +3 more
europepmc   +1 more source

Body Size Modulates the Impact of the Dispersive Patch Position During Radiofrequency Cardiac Ablation. [PDF]

Bioengineering (Basel)
Irastorza RM, Berjano E.
europepmc   +1 more source

Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework. [PDF]

EBioMedicine
Mostert CM, Udeh-Momoh C, Winkler AS, McLaughlin C, Eyre H, Salama M, Ranchod K, Trepel D, Vradenburg G, Hynes W, Fieggen G, Ali S, Mekkaoui NEL, Landay A, Bobrow K, Muyela L, Atkins K, Chadha AS, Marongiu R, Barbato M, Nightingale S, Joska J, Njamnshi AK, Rizig M, Kahn JG, Blackmon K, Merali Z, Ibanez A.   +27 more
europepmc   +1 more source

Correction: Some new evidence using fractional integration about trends, breaks and persistence in polar amplification. [PDF]

Sci Rep
Caporale GM, Gil-Alana LA, Carmona-González N.   +2 more
europepmc   +1 more source