Results 51 to 60 of about 209 (116)

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

MedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye, Changmin Kim, Minah Jeon, Yeji Yoon, Jiyoon Park, Ryun Hee Lee, Carson Yu, Ho Seok Chung, Jae Yong Kim, David Myung, Hun Lee   +10 more
wiley   +1 more source

Herpes Simplex Virus endotheliitis following descemet‘s membrane endothelial keratoplasty

Journal of Ophthalmic & Vision Research, 2015
Purpose: To report a case of herpes simplex virus (HSV) endotheliitis following simultaneous phacoemulsification, intraocular lens (IOL) implantation and descemet‘s membrane endothelial keratoplasty (DMEK).
Siamak Zarei-Ghanavati1, Reza Alizadeh, Sonia H Yoo   +2 more
doaj   +1 more source

Placoid choroidopathy after bilateral uncomplicated descemet's membrane endothelial keratoplasty

American Journal of Ophthalmology Case Reports, 2020
Purpose: To describe a case of bilateral, sequential placoid choroidopathy following uncomplicated Descemet's membrane endothelial keratoplasty (DMEK).
Thomas H. Dohlman, Neepa Shah, Colin Prensky, Mrinali P. Gupta, Donald J. D'Amico, Szilard Kiss, Christopher S. Sales   +6 more
doaj   +1 more source

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

Acta Ophthalmologica, Volume 104, Issue 2, Page e183-e190, March 2026.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl, Leonie Bourauel, Benjamin Aretz, Diana Samarghitan, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca   +8 more
wiley   +1 more source

Preloaded Tissues for Descemet Membrane Endothelial Keratoplasty

American Journal of Ophthalmology, 2016
To determine the feasibility of preloading endothelial tissues for Descemet membrane endothelial keratoplasty (DMEK).Laboratory investigation.setting: Institutional.Twenty human donor corneas unsuitable for transplantation with endothelial cell density in a range of 1600-2700 cells/mm(2).The endothelium was punched, stripped (8.5 mm diameter) and ...
Parekh, Mohit, Ruzza, Alessandro, Ferrari, Stefano, Busin, Massimo, Ponzin, Diego   +4 more
openaire   +3 more sources

Effects of COVID‐19 on Corneal Transplants Across the Five Regions of Brazil and Trends in Post‐Pandemic Recovery—A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims The COVID‐19 pandemic significantly disrupted global eye health services, including corneal transplants. This study evaluates the pandemic's long‐term impact on corneal transplantation across Brazil's five regions, highlighting national and regional recovery trends.
Josue Geraldo Lessa, Amélia Soares de Melo, Leandro Vassuler Baldon, Bernardo G. L. Carvalho, Nathalia Sernizon Guimaraes, Aleida N. Soares, Bruno Lovaglio Cançado Trindade, Fernanda Ludolf   +7 more
wiley   +1 more source

Descemet’s membrane endothelial keratoplasty in aphakic and vitrectomized eye

GMS Ophthalmology Cases, 2020
Objective: To report a new technique for Descemet’s membrane endothelial keratoplasty (DMEK) in aphakic and vitrectomized eyes. Case description: A 56-year-old man presented with corneal decompensation in the left eye after combined pars plana vitrectomy
Karadag, Remzi, Aykut, Veysel, Esen, Fehim, Oguz, Halit, Demirok, Ahmet   +4 more
doaj   +1 more source

Quality of life and participation after corneal transplantation and potential predictors: A multicenter prospective cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 52-64, February 2026.
Abstract Purpose To evaluate the long‐term effect of corneal transplantation on health‐ and vision‐related quality of life, visual functioning, and societal participation, and to assess potential predictors. Methods We conducted a multicenter prospective cohort study in 11 Dutch hospitals and eye clinics.
E. B. M. Elsman, D. Van der Meij, H. P. A. Van der Aa, N. Santana, M. C. Bartels, M. Zaal, Y. Y. Cheng, R. M. M. A. Nuijts, G. H. M. B. Van Rens, R. M. A. Van Nispen   +9 more
wiley   +1 more source

The incidence of serious complications after selective laser trabeculoplasty

Acta Ophthalmologica, Volume 104, Issue 1, Page 106-113, February 2026.
Abstract Purpose To evaluate the incidence of serious complications after selective laser trabeculoplasty (SLT). Methods All patients who underwent SLT at the Department of Ophthalmology, Helsinki University Hospital, were eligible for the study from 1 January 2012 to 31 December 2018.
Eeva S. Ojanen, Joni A. Turunen, Mika Harju   +2 more
wiley   +1 more source