Results 91 to 100 of about 384,561 (284)

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén   +16 more
wiley   +1 more source

19. AORTIC DISTENSIBILITY IS MORE CLOSELY ASSOCIATED WITH CAROTID INTIMA MEDIA THICKNESS THAN AORTIC INTIMA-MEDIA THICKNESS IN THE PATIENTS WITH ISCHEMIC STROKE

open access: yesArtery Research, 2009
Background: The aorta plays a central role for a modulator in whole cardiovascular system by its elasticity. If the elasticity was decreased, aortic distensibility was also decreased and stiffness index was elevated.
Hyun Ju Yoon   +9 more
doaj   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

open access: yesESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori   +9 more
wiley   +1 more source

Local Search and the Evolution of World Models

open access: yesTopics in Cognitive Science, EarlyView., 2023
Abstract An open question regarding how people develop their models of the world is how new candidates are generated for consideration out of infinitely many possibilities. We discuss the role that evolutionary mechanisms play in this process. Specifically, we argue that when it comes to developing a global world model, innovation is necessarily ...
Neil R. Bramley   +3 more
wiley   +1 more source

Growth Rate Assessed by Vascular Deformation Mapping Predicts Type B Aortic Dissection in Marfan Syndrome

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Patients with Marfan syndrome (MFS) are at a high risk of type B aortic dissection (TBAD). Aortic growth and elongation have been suggested as risk factors for TBAD.
Carlos Alberto Campello Jorge   +7 more
doaj   +1 more source

First evaluation of a novel pulsatile LVAD: Feasibility and haemodynamic impact in acute heart failure

open access: yesESC Heart Failure, EarlyView.
The pulsatile ventricular assist platform (pVAP) was connected to a membrane pump in six large swine models. The system, driven by a conventional intra‐aortic balloon pump console (IABP), was utilized to drain left atrial blood during systole and to eject the collected blood back into the ascending aorta during diastole.
Sara Knigge   +11 more
wiley   +1 more source

Aneurismas da aorta Aortic aneurysms

open access: yesBrazilian Journal of Cardiovascular Surgery, 1992
Entre janeiro de 1979 e janeiro de 1992, foram realizadas 212 operações para correção de aneurismas e de dissecções da aorta. Neste trabalho serão analisados 104 procedimentos cirúrgicos (em 97 pacientes) para correção de aneurismas.
Januário M Souza   +8 more
doaj  

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

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