Results 41 to 50 of about 39,482 (228)

Stricture of the descending colon due to schistosomiasis [PDF]

Postgraduate Medical Journal, 1976
Summary An example of a localized non-fibrous stricture of the colon due to Schistosoma mansoni infection is reported. The radiological and colonoscopic features are described. After treatment of the infection with niridazole, the stricture resolved completely. The pathogenesis of bowel lesions in schistosomiasis is briefly discussed.
S G, Wright, P, Renton, E T, Swarbrick
openaire   +2 more sources

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

The pattern of lymph node metastasis and the outcome of high and low dissection in descending colon cancer

Asian Journal of Surgery
Background/objectives: Few studies focused on the distribution of lymph node metastasis and outcomes of different dissection levels in descending colon cancer.
Yu-Zu Lin, Yi-Wen Yang, Che-Yuan Chang, Hou-Hsuan Cheng, Sheng-Chieh Huang, Hung-Hsin Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Jeng-Kai Jiang, Shih-Ching Chang   +11 more
doaj   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Coiled Descending Colon with Persistent Mesocolon and a Straight Sigmoid Colon – An Unique Congenital Anomaly

Online Journal of Health & Allied Sciences, 2016
Descending colon is a retroperitoneal part of colon extending from left colic flexure to the brim of pelvis. Rarely does it have a mesocolon. Descending colon is most commonly affected by ulcerative colitis, Crohn’s disease and colon cancer.
Satheesha Nayak B, Ravindra S Swamy, Ashwini Aithal P, Ashwini Aithal P   +3 more
doaj  

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Metachronous adenocarcinoma and large cell neuroendocrine carcinoma of the colon

Formosan Journal of Surgery, 2018
Neuroendocrine tumors are a group of heterogeneous tumors originating from peptidergic neurons and neuroendocrine cells and can occur in many organs and tissues of the body.
Kung-Hung Lin, Nai-Jen Chang, Li-Ren Liou, Ming-Shan Su, Min-Jen Tsao, Meng-Lin Huang   +5 more
doaj   +1 more source

Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats [PDF]

Acta Cirúrgica Brasileira, 2006
PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study.
Feng Chung Wu, Huei Diana Lee, Maksoel Algustin Krauspenhar Niz, Maria de Loudes Setsuko Ayrizono, Cláudio Saddy Rodrigues Coy, Juvenal Ricardo Navarro Góes, João José Fagundes   +6 more
doaj   +1 more source

Optimal Indication of D3 Lymph Node Dissection for Non‐Metastatic Colon Cancers by Tumor Stages: Evaluation of Therapeutic Value Index for Each Lymph Node Station

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aims To explore the therapeutic impact of D3 lymph node dissection for non‐metastatic colon cancers, evaluating the therapeutic value index for each lymph node station according to surgical stages. Methods Consecutive patients with surgical Stage I–III colon and rectosigmoid cancer who underwent curative resection between January 2003 and ...
Akira Ouchi, Kozo Kataoka, Eiji Shinto, Takashi Akiyoshi, Takefumi Yoshida, Yasuyuki Takamizawa, Yukihide Kanemitsu, Hirotoshi Kobayashi, Hideki Ueno, on behalf of the Lymph Nodes Committee of JSCCR   +9 more
wiley   +1 more source

Prevalence of MSI‐H/dMMR Colorectal Cancer in Japan: Data From the Clinical Study Group of the University of Osaka‐Colorectal Registry

Annals of Gastroenterological Surgery, EarlyView.
Using a multicenter Japanese colorectal cancer cohort from 25 institutions, we analyzed 1464 patients across all disease stages and tumor locations to determine the prevalence and clinicopathological features of MSI‐H/dMMR colorectal cancer. MSI‐H/dMMR tumors accounted for 9.4% of cases overall, were present in 22% of right‐sided colon cancers, and ...
Yoshihiro Morimoto, Mamoru Uemura, Yoshinori Kagawa, Hidekazu Takahashi, Masayuki Hiraki, Yozo Suzuki, Shinichi Yoshioka, Mitsuyoshi Tei, Shu Okamura, Yukako Mokutani, Atsushi Naito, Shinji Tokuyama, Takamichi Komori, Akinobu Yasuyama, Genta Sawada, Yujiro Fujie, Shinya Yamashita, Naotsugu Haraguchi, Yusuke Matsuura, Chu Matsuda, Yoshinao Chinen, Tatsushi Shingai, Katsuki Danno, Nobuo Tanaka, Kazuya Sakata, Kohei Murata, Yuichiro Doki, Hidetoshi Eguchi   +27 more
wiley   +1 more source