Results 191 to 200 of about 11,164,814 (363)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Design and validation of a flexible framework for developing generic digital twins for Industry 4.0. [PDF]

Sci Rep
Pribiš R, Drahoš P, Kozák Š, Beňo L, Kučera E, Haffner O, Pajpach M.   +6 more
europepmc   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

VegVault dataset: linking global paleo-, and neo-vegetation data with functional traits and abiotic drivers. [PDF]

Sci Data
Mottl O, Gaiser F, Šímová I, Flantua SGA.   +3 more
europepmc   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Proposal of two novel species, <i>Allocoprococcus similis</i> gen. nov., sp. nov. and <i>Faecalimonas hominis</i> sp. nov., isolated from human faeces and genome-based reorganization of the genus <i>Coprococcus</i>. [PDF]

Int J Syst Evol Microbiol
Yamamoto E, Hisatomi A, Miwa K, Sakurai N, Koizumi A, Ohkuma M, Tsuchihashi H, Sakamoto M.   +7 more
europepmc   +1 more source

Multinuclear PFGSTE NMR description of 39K, 23Na, 7Li, and 1H specific activation energies governing diffusion in alkali nitrite solutions

Trent R. Graham, Ashley R. Kennedy, Robert G. Felsted, Roberto A. Colina-Ruiz, Emily T. Nienhuis, Jacob G. Reynolds, Carolyn I. Pearce   +6 more
openalex   +2 more sources

A typology for the classification, description and valuation of ecosystem functions, goods and services

, 2002
R. Groot, M. Wilson, R. Boumans
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

XI.—Descriptions of species of Asteriidæ and Ophiuridæ from Kerguelen's Island

, 1876
Edgar A. Smith
openalex   +2 more sources