Results 41 to 50 of about 71,112 (263)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Maximum Entropy Reasoning via Model Counting in (Description) Logics that Count

Proceedings of the International Florida Artificial Intelligence Research Society Conference
In previous work it was shown that the logic ALCME,  which extends the description logic (DL) ALC with probabilistic conditionals, has domain-lifted inference.
Franz Baader, Anton Claußnitzer
doaj   +1 more source

Engineering Support for Handling Controller Conflicts in Energy Storage Systems Applications

Energies, 2017
Energy storage systems will play a major role in the decarbonization of future sustainable electric power systems, allowing a high penetration of distributed renewable energy sources and contributing to the distribution network stability and reliability.
Claudia Zanabria, Ali Tayyebi, Filip Pröstl Andrén, Johannes Kathan, Thomas Strasser   +4 more
doaj   +1 more source

Reconciling description logics and rules [PDF]

Journal of the ACM, 2008
Description logics (DLs) and rules are formalisms that emphasize different aspects of knowledge representation: whereas DLs are focused on specifying and reasoning about conceptual knowledge, rules are focused on nonmonotonic inference. Many applications, however, require features of both DLs and rules.
Boris Motik, ROSATI, Riccardo
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

MP-HTHEDL: A Massively Parallel Hypothesis Evaluation Engine in Description Logic

IEEE Access
We present MP-HTHEDL, a massively parallel hypothesis evaluation engine for inductive learning in description logic (DL). MP-HTHEDL is an extension on our previous work HT-HEDL, which also targets improving hypothesis evaluation performance for inductive
Eyad Algahtani
doaj   +1 more source

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

A Benchmark on Reliability of Complex Discrete Systems: Emergency Power Supply of a Nuclear Power Plant [PDF]

Electronic Proceedings in Theoretical Computer Science, 2017
This paper contains two parts: the description of a real electrical system, with many redundancies, reconfigurations and repairs, then the description of a reliability model of this system, based on the BDMP (Boolean logic Driven Markov Processes ...
Marc Bouissou
doaj   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Ontology Driven Analysis of Spatio-temporal Phenomena, Aimed At Spatial Planning And Environmental Forecasting [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013
Spatial planning is a crucial area for balancing civilization development with environmental protection. Spatial planning has a multidisciplinary nature.
A. Iwaniak, J. Łukowicz, M. Strzelecki, I. Kaczmarek   +3 more
doaj   +1 more source