Results 201 to 210 of about 16,858,520 (353)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Sexual harassment complaints across BSE100 companies: a longitudinal dataset (2013-2023). [PDF]

BMC Res Notes
R D, Nath V GR.
europepmc   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Biodata Mobilisation of the Entomological Collections of the Schmalhausen Institute of Zoology of the National Academy of Sciences of Ukraine. [PDF]

Biodivers Data J
Babytskiy A, Kaliuzhna M, Varga O, Kavurka V, Prokhorov A, Kletionkin V, Martynova K, Nuzhna A, Klymenko S, Fursov V, Parkhomenko M.   +10 more
europepmc   +1 more source

Erratum: Nucleon-number-conserving description of pairing correlations in terms of occupation probability amplitudes [PDF]

, 1988
M. Hasegawa, S. Tazaki
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

A dataset of the abundance of <i>Ixodes</i> spp. ticks in forests of the Auvergne-Rhône-Alpes Region (France). [PDF]

Biodivers Data J
Lebert I, Poux V, René-Martellet M, Chalvet-Monfray K, Vourc'h G, Bord S.   +5 more
europepmc   +1 more source

Some models of lattice-gas class related with population number description [PDF]

, 2000
V. G. Anfinogentov, А. А. Короновский, Alexander E. Hramov   +2 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Application of the Bidirectional Encoder Representations from Transformers Model for Predicting the Abbreviated Injury Scale in Patients with Trauma: Algorithm Development and Validation Study. [PDF]

JMIR Form Res
Tang J, Li Y, Luo K, Lai J, Yin X, Wu D.
europepmc   +1 more source