Results 161 to 170 of about 2,711,555 (278)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prevalence and Characteristics of Twitter Posts About Court-Ordered, Tobacco-Related Corrective Statements: Descriptive Content Analysis.

JMIR Public Health Surveill, 2019
Kelley DE, Brown M, Murray A, Blake KD.
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Information Quality, Content Scope, and Audience Engagement of Popular Turkish Instagram Posts on Tooth Whitening: A Cross-Sectional Content Analysis. [PDF]

Healthcare (Basel)
Yılmaz NA, Akkoçan BA, Akkoçan O, Ulucan SE.   +3 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Effect of Carnosine Supplementation on Warmed-Over Flavor, Volatile Compounds, and Meat Quality in Ground Chicken Breast and Thigh Meat. [PDF]

J Poult Sci
Watanabe G, Ishida S, Akada K, Komatsu M, Sakurai H, Shinoda S, Motoyama M, Nakajima I, Asano A, Miyaguchi Y, Sasaki K.   +10 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Quality and reliability of diabetic nephropathy-related videos on TikTok and Bilibili: A cross-sectional content analysis. [PDF]

Medicine (Baltimore)
Wang M, Wang X, Gong B.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Social media activities to enhance the visibility of long-term invasive ventilation: A content and visibility analysis from the PRiVENT study. [PDF]

PLoS One
Trudzinski FC, Litke N, Buntemeyer O, Janssen S, Biehler E, Fleischhauer T, Dahlhoff JC, Höger P, Kempa A, Neetz B, Joves B, Neurohr C, Ghiani A, Schneider A, Szecsenyi J, Meis J, Schubert-Haack J, Michels-Zetsche JD, Herth FJ, and the PRiVENT-Study Group.   +19 more
europepmc   +1 more source