Results 71 to 80 of about 3,310,600 (279)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Observance of national ethics codes of medical research in undergraduate doctoral dissertations in the Faculty of Dentistry, Islamic Azad University, Khorasgan Branch in 2004-2009

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2012
Introduction: Observance of ethical codes in dental research has received little attention. This research aims to evaluate observance of national research ethics codes in research proceedings of doctoral dissertations in the Faculty of Dentistry, Islamic
Arash Ghodousi   +4 more
doaj  

Description of a Skills Oriented Health Ethics Program

open access: yesAmerican Journal of Pharmaceutical Education, 1984
Continuing change requires that the primary goal of ethics education be the development of competencies to address changing ethical issues. To develop the skill of critical ethical thinking, a two component model was developed. The first component is a two semester hour course in ethical theory.
J, LeFevre, P, Miederhoff
openaire   +2 more sources

Welcome to the Ohio Ethics Commission

open access: yes, 2008
Title from caption of web page (viewed on Apr.
Ohio Ethics Commission.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Ethics Eye නිරීක්ෂකයෙකු වන්න ඔබටත් පුළුවන්!

open access: yes
This entry includes only three infographics (in Sinhala) and no writeups.On January 8, 2024, the Ethics Eye team published a three-slide post on their facebook page encouraging followers and others to join the team as external media ethics violation ...
Ethics Eye
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Compliance with Organizational Professioanal Codes of Ethics by the Iran Public Libraries Foundation Staff in Yazd Province [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2013
Purpose: This research examined the  compliance with of professional codes of ethics public library staff  in the province of Yazd in years 2010-2011. Methodology: The research method is descriptive.
Mosayeb Rezaei   +3 more
doaj  

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