Results 21 to 30 of about 18,180 (265)

CONTRIBUTIONS FOR DEVELOPING OF A COMPUTER AIDED LEARNING ENVIRONMENT OF DESCRIPTIVE GEOMETRY

open access: yesJournal of Industrial Design and Engineering Graphics, 2009
The paper presents the authors’ contributions for developing a computer code for teaching of descriptive geometry using the computer aided learning techniques.
Antonescu Ion   +2 more
doaj  

General Explicit Solution of Planar Weakly Delayed Linear Discrete Systems and Pasting Its Solutions

open access: yesAbstract and Applied Analysis, 2014
Planar linear discrete systems with constant coefficients and delays x(k+1)=Ax(k)+∑l=1n‍Blxl(k-ml) are considered where k∈ℤ0∞:={0,1,…,∞}, m1,m2,…,mn are constant integer delays ...
Josef Diblík, Hana Halfarová
doaj   +1 more source

Shape Dependent EMA Model of Nanostructured Anisotropic Materials

open access: yesNanomaterials, 2019
Heterogeneous nanostructures containing nanoparticles of various sizes and shapes have attracted significant attention in the development of nano-biosensors.
Petr Otipka, Jaroslav Vlček
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Representation of the Solutions of Linear Discrete Systems with Constant Coefficients and Two Delays

open access: yesAbstract and Applied Analysis, 2014
The purpose of this paper is to develop a method for the construction of solutions to initial problems of linear discrete systems with constant coefficients and with two delays Δx(k)=Bx(k-m)+Cx(k-n)+f(k), where m,n∈ℕ, m≠n, are fixed, k=0,…,∞, B=(bij), C=(
Josef Diblík, Blanka Morávková
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

SIGNS LANGUAGE IN GRAPHICAL COMMUNICATION MECHANICAL DRAWING: THE BASIC LANGUAGE IN GRAPHICAL COMMUNICATION

open access: yesJournal of Industrial Design and Engineering Graphics, 2010
The paper presents general notions about graphical language used in engineering, the international standards used for representing objects and also the most important software applications used in Computer Aided Design for the development of products in ...
BADEA Florina, PETRESCU Ligia
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

THE DESIGN AND IMPLEMETATION OF THE RESEARCH CENTER FOR AERONAUTICS AND SPACE WEB SITE

open access: yesJournal of Industrial Design and Engineering Graphics, 2010
This paper presents some elements and principles commonly used in web design. It’s addressed to anyone with an interest in developing their skills as a visual communicator, anyone who wants to learn the basics of graphical design, so they can develop ...
LEHADUS Daniel, SIMION Ionel
doaj  

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