Results 141 to 150 of about 3,596,410 (291)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Descriptive Representation and Reproductive Health Outcomes: The Role of Women Candidates in Reducing Teen Birth Rates. [PDF]

Healthcare (Basel)
Cortina J, Hardin S.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Immigrant integration policies and descriptive political representation

, 2016
peer reviewedThis chapter addresses the extent to which the political opportunity structure (POS) in European democracies affects the outcomes of descriptive political representation of citizens of immigrant origin (CIOs) in national parliaments.
Schwemmer, Carsten, Guerra, Simona, Konstantinidou, Angeliki, Vintila, Cristina-Daniela   +3 more
core   +1 more source

Reconfiguration of Descriptive Representation of Information in Digital Informational Ecosystems: Interoperability, Automation, and Artificial Intelligence

Advances in Knowledge Representation
The digital transformation of informational environments has promoted significant changes in descriptive representation, especially through semantic interoperability, metadata automation, and the growing use of artificial intelligence.
Célia Dias, Alexandre Rocha, Isabella de Brito Alves, Cleide Faria   +3 more
doaj  

Racial and Ethnic Composition of the U.S. Emergency Medicine Workforce, Change From 2013 to 2023. [PDF]

Acad Emerg Med
Gettel CJ, Gottlieb M, Calderon Y, Diercks DB, Lall MD, Rothenberg C, Agrawal P, Venkatesh AK.   +7 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Gender Representation at Turkish Anaesthesiology and Reanimation Congresses: Trends in Speakers, Session Chairs, and Society Leadership from 2015 to 2024. [PDF]

Turk J Anaesthesiol Reanim
Öner SF, Şenol Karataş S.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Ideomotor representation, motor control, and body aesthetics in juvenile rhythmic gymnasts: between reciprocal support and differentiated trajectories within a personalized training program. [PDF]

Front Sports Act Living
Ciorășteanu RM, Mijaica R, Balint L.
europepmc   +1 more source