Results 191 to 200 of about 1,939,299 (336)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Grounding digital mental health and wellbeing platform development in a theory of change: a convergent mixed methods approach. [PDF]

Front Psychiatry
Cowling EP, Misch R, Sugarman G, Sammut S, Hanley T, Sugarman R, Green L, Johnston P, Ramos T, Rock B, Wilson H, Salhi L.   +11 more
europepmc   +1 more source

Generalized Descriptive Set Theory at Singular Cardinals of Countable Cofinality [PDF]

Vincenzo Dimonte, Luca Motto Ros
openalex   +1 more source

The axiom of determinacy and the modern development of descriptive set theory [PDF]

, 1988
Vladimir Kanovei
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Robustness is better assessed with a few thoughtful models than with billions of regressions. [PDF]

Proc Natl Acad Sci U S A
Auspurg K.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

A rational information gathering account of infant habituation. [PDF]

Behav Neurosci
Karni G, Mattar MG, Emberson L, Daw ND.
europepmc   +1 more source

Three Creative Tensions in Document Interpretation Theory Set as Evidence of the Need for a Descriptive Informatics

, 2009
Joseph T. Tennis
openalex   +1 more source

Topics in descriptive set theory related to equivalence relations, complex borel and analytic sets [PDF]

, 2017
Nikolaos E. Sofronidis
openalex   +1 more source