Results 91 to 100 of about 274,523 (304)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Technical interoperability between semantic and descriptive standards: working with distributed thesauri through the Web [PDF]

, 2013
[Resumen] La presente comunicación describe un caso práctico donde se utiliza la especificación técnica SRU (Search/ Retrieve URL) para acceder a vocabularios controlados remotos codificados en SKOS, concretamente a los thesauri de Ingeniería publicados ...
Eito Brun, Ricardo
core  

Pandangan Masyarakat Terhadap Kebijakan Standar Nasional Pendidikan (Studi Pada Pendidikan Dasar di Kota Tanjungpinang)

Jurnal Ilmu Pemerintahan, 2017
Education problems related to the issue of state goals is educating the nation. Therefore, the Government should establish a policy on optimal standard of education for its society.
Rendra Setyadiharja, Neng Suryanti Nengsih   +1 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

EBI metagenomics—a new resource for the analysis and archiving of metagenomic data [PDF]

, 2013
Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil ...
Vaughan, Daniel, Mitchell, Alex, Field, Dawn, Gonzalez-Beltran, Alejandra, Scheremetjew, Maxim, McAnulla, Craig, Sansone, Susanna-Assunta, Sterk, Peter, Radhakrishnan, Rajesh, Hunter, Sarah, Leinonen, Rasko, Jones, Philip, Jones Philip, Denise, Hubert, Cochrane, Guy, Maslen, John, Oisel, Arnaud, Pesseat, Sebastien, Hubert, Denise, Corbett, Matthew, Fraser, Matthew, Rocca-Serra, Philippe, Hunter, Christopher, Michell, Alex, Maguire, Eamonn, Gift, Nuka, Nuka, Gift   +26 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

A Descriptive Review of ANSI-NISO Standards with Specific Reference to Their Implications for Digital Library Systems (2015-2023)

Journal of Information Science Theory and Practice
This paper provides a systematic review of American National Standards Institute-National Information Standards Organization (ANSI-NISO) standards that have been published or revised since 2015, and the aim of the paper is to review them in terms of ...
Lili Sahu, Bulu Maharana
doaj   +1 more source