Results 271 to 280 of about 560,036 (321)

Two-Stage Probability-Enhanced Regression on Property Matrices and LLM Embeddings Enables State-of-the-Art Prediction of Gene Knockdown by Modified siRNAs. [PDF]

Int J Mol Sci
Golovkin I, Shatkovskii D, Serov N.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

HybridSense-LLM: A Structured Multimodal Framework for Large-Language-Model-Based Wellness Prediction from Wearable Sensors with Contextual Self-Reports. [PDF]

Bioengineering (Basel)
Yu CH, Masum M.
europepmc   +1 more source

Validation and implementation of hydration and mechanical descriptors of stratum corneum ex vivo and in vivo

, 2013
Raoul Vyumvuhore
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

PepScorer::RMSD: An Improved Machine Learning Scoring Function for Protein-Peptide Docking. [PDF]

Int J Mol Sci
Cavalli AG, Vistoli G, Pedretti A, Fumagalli L, Mazzolari A.   +4 more
europepmc   +1 more source

Development of Ensemble Steric and Electrostatic Chirality (ESEC) descriptors for modelling chromatographic enantioseparations. [PDF]

PLoS One
Peeters J, De Gauquier P, Ameli F, Heyden YV, Mangelings D, Vanommeslaeghe K.   +5 more
europepmc   +1 more source

Estimating room acoustic descriptors from bag-of-vectors representation with transformers

Bence E. Bakos, Gábor Hidy, Bálint Csanády, Csaba Huszty, András Lukács   +4 more
openalex   +1 more source

Predictive power of parametric temperature based topological indices with applications in structure property modeling of anti tuberculosis drugs. [PDF]

Sci Rep
Hayat S, Alanazi SJF, Belay MB, Wang S.
europepmc   +1 more source

Integrated Biomimetic 2D-LC and Permeapad^® Assay for Profiling the Transdermal Diffusion of Pharmaceutical Compounds. [PDF]

Molecules
Neri I, Stevens C, Russo G, Grumetto L.
europepmc   +1 more source