Results 31 to 40 of about 127,767 (267)

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Common European Framework of Reference for Languages in Croatia: an analysis of writing competence at level C1

open access: yesLinguistica, 2014
The aim of the article is to present the results of a research conducted with advanced (C1 level) learners of French as a foreign language in Croatia, in which their writing competence was studied according to the CEFR descriptors.
Marija Spajić, Yvonne Vrhovac
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Data-Driven and Structure-Based Modelling for the Discovery of Human DNMT1 Inhibitors: A Pathway to Structure–Activity Relationships

open access: yesApplied Sciences
Nowadays, the explosive growth of knowledge in the epigenetics field has highlighted DNA methyltransferase 1 (DNMT1) as a key regulator of genomic methylation patterns and a promising therapeutic target in several diseases.
Paris Christodoulou   +7 more
doaj   +1 more source

Vacancy Formation Energy as an Effective Descriptor for the Catalytic Oxidation of CO by Au Nanoparticles

open access: yesMetals, 2023
Gold nanoparticles (AuNPs) have attracted wide attention in the field of catalysis because of their excellent stability and electrical properties. Herein, an accurate vacancy formation energy model based on nanothermodynamics theory is developed, the ...
Zhiwei Zhang   +5 more
doaj   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

Listening to Teachers: CEFR implementation in University Language Centres in Spain

open access: yesRevista de Lingüística y Lenguas Aplicadas
Despite the widespread reference to the Common European Framework of Reference for Languages (CEFR) and the Companion Volume (CV) in the language teaching curriculum in Spain, there is no information regarding teachers’ familiarity with the documents and
Gloria Luque Agulló   +1 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Foreign Language Mediation Activities in the Dialogue of Cultures

open access: yesVestnik MGIMO-Universiteta, 2015
The article addresses the CEFR extended set of language proficiency descriptors. The author points out that education, as well as the language, make an integral part of national culture and reflect the problems existing in society including the problems ...
Elena V. Voevoda
doaj   +2 more sources

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

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