Results 11 to 20 of about 39,003 (93)

Risk and location of distant metastases in patients with locally advanced rectal cancer after total neoadjuvant treatment or chemoradiotherapy in the RAPIDO trial.

European Journal of Cancer, 2023
INTRODUCTION Although optimising rectal cancer treatment has reduced local recurrence rates, many patients develop distant metastases (DM). The current study investigated whether a total neoadjuvant treatment strategy influences the development, location,
R. Bahadoer, G. Hospers, C. Marijnen, K. Peeters, H. Putter, E. Dijkstra, E. Kranenbarg, A. Roodvoets, B. van Etten, P. Nilsson, B. Glimelius, C. J. van de Velde   +11 more
semanticscholar   +1 more source

The value of post-operative chemotherapy after chemoradiotherapy in patients with high-risk locally advanced rectal cancer—results from the RAPIDO trial

ESMO Open, 2023
Background Pre-operative chemoradiotherapy (CRT) rather than radiotherapy (RT) has resulted in fewer locoregional recurrences (LRRs), but no decrease in distant metastasis (DM) rate for patients with locally advanced rectal cancer (LARC).
E. Dijkstra, W. Zwart, P. Nilsson, H. Putter, A. Roodvoets, E. Meershoek-Klein Kranenbarg, J. Frödin, P. Nygren, L. Østergaard, C. Kersten, I. Verbiéné, A. Cervantes, M. Hendriks, J. Capdevila, I. Edhemovic, C. van de Velde, C. Marijnen, B. van Etten, G. Hospers, B. Glimelius   +19 more
semanticscholar   +1 more source

Quality of life and late toxicity after short-course radiotherapy followed by chemotherapy or chemoradiotherapy for locally advanced rectal cancer - the RAPIDO trial.

Radiotherapy and Oncology, 2022
BACKGROUND AND PURPOSE The RAPIDO trial demonstrated a decrease in disease-related treatment failure (DrTF) and an increase in pathological complete responses (pCR) in locally advanced rectal cancer (LARC) patients receiving total neoadjuvant treatment ...
E. Dijkstra, G. Hospers, E. Meershoek-Klein Kranenbarg, J. Fleer, A. Roodvoets, R. Bahadoer, M. Guren, J. Tjalma, H. Putter, R. Crolla, M. Hendriks, J. Capdevila, C. Radu, C. van de Velde, P. Nilsson, B. Glimelius, B. van Etten, C. Marijnen   +17 more
semanticscholar   +1 more source

The role of total neoadjuvant therapy in locally advanced rectal cancer: a survey of specialists attending the All-Ireland Colorectal Cancer Conference 2022 including lead investigators of OPRA, PRODIGE-23 and RAPIDO

Irish Journal of Medical Science, 2023
The treatment of locally advanced rectal cancer (LARC) has evolved following recent landmark trials of total neoadjuvant therapy (TNT)—the delivery of preoperative chemotherapy sequenced with radiation.
Timothy O’Brien, G. Hospers, T. Conroy, Heinz-Josef Lenz, J. Smith, E. Andrews, Brian O'Neill, Greg Leonard   +7 more
semanticscholar   +1 more source

Comment on “Locoregional Failure During and After Short-Course Radiotherapy Followed by Chemotherapy and Surgery Compared to Long-Course Chemoradiotherapy and Surgery: A Five-Year Follow-Up of the RAPIDO Trial”: The RAPIDO Trial Does Not Achieve Its Primary Endpoint

Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2023
e congratulate the Rectal cancer And Pre-operative Induction therapy followed by Dedicated Operation (RAPIDO) investigators for their large randomized trial that showed a significant reduction in the 5-year metastatic rate with total neoadjuvant therapy ...
O. Riou, S. Gourgou, T. Conroy
semanticscholar   +1 more source

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial.

The Lancet Oncology, 2020
BACKGROUND Systemic relapses remain a major problem in locally advanced rectal cancer. Using short-course radiotherapy followed by chemotherapy and delayed surgery, the Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation ...
R. Bahadoer, E. Dijkstra, B. van Etten, C. Marijnen, H. Putter, E. Kranenbarg, A. Roodvoets, I. Nagtegaal, R. Beets-Tan, L. Blomqvist, T. Fokstuen, A. T. Ten Tije, J. Capdevila, M. Hendriks, I. Edhemovic, A. Cervantes, P. Nilsson, B. Glimelius, C. J. van de Velde, G. Hospers   +19 more
semanticscholar   +1 more source

Projeto básico de estação de tratamento de água para reúso de efluente da lavagem de veículos em lava-rápido

Cadernos Técnicos Engenharia Sanitária e Ambiental, 2023
O presente trabalho teve como objetivo a elaboração de um projeto básico de engenharia de uma estação de tratamento de água para reúso de efluente da lavagem de veículos em um lava-rápido da cidade de São Paulo, em atendimento ao Decreto Municipal nº 56 ...
João Lucas Melo de Oliveira, Andressa Duarte Gil, Antônio Fábio Silva Santos, Thaynara Ribeiro Felismino, Alexandre Saron   +4 more
semanticscholar   +1 more source

Is short-course radiotherapy and total neoadjuvant therapy the new standard of care in locally advanced rectal cancer? A sensitivity analysis of the RAPIDO clinical trial.

Annals of Oncology, 2022
BACKGROUND The results of the RAPIDO trial have been accepted as evidence in favor of short-course radiotherapy (SC-RT) followed by chemotherapy before total mesorectal excision in high-risk locally advanced rectal cancer.
P. Jimenez-Fonseca, R. Salazar, V. Valentí, P. Msaouel, A. Carmona-Bayonas   +4 more
semanticscholar   +1 more source

The potential of primary health care in the consolidation of the of the anti-hiv rapid test: discourse analysis / Potencialidades da atenção primária à saúde na consolidação do teste rápido anti-HIV: análise do discurso

Revista de Pesquisa : Cuidado é Fundamental Online, 2022
Objetivo: Analisar o discurso dos gerentes de saúde a respeito das potencialidades para realização do Teste Rápido anti-HIV na Atenção Primária à Saúde.
Haline Costa dos Santos Guedes, José Nildo de Barros Silva Júnior, D. C. Januário, Alexsandra de Luna Freire Holanda, Viviane Michele Silva, Anne Jaquelyne Roque Barrêto   +5 more
semanticscholar   +1 more source

InFaRR: Um algoritmo para reroteamento rápido em planos de dados programáveis

Brazilian Symposium on Computer Networks and Distributed Systems, 2022
O InFaRR (In-network Fast ReRouting) é um algoritmo para reroteamento rápido implementado em P4, apresenta quatro características não encontradas, de maneira conjunta, em outros mecanismos de recuperação: prevenção de loop, pushback, aprendizagem e ...
Gustavo V. Luz, André L. B. Rocha, L. Almeida, Fábio L. Verdi   +3 more
semanticscholar   +1 more source