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Patient and Graft Outcome Among High Immunologic Risk Renal Transplant Recipients
Transplantation, 2018Introduction Kidney transplantation (KT) is the preferred treatment for ESRD. However, some patients had prior HLA sensitization making them immunologically high risk for graft rejection and poorer graft survival.
J. Mora +3 more
semanticscholar +1 more source
Insulin allergy. Clinical and immunological effects of specific desensitization
Acta Diabetologica Latina, 1969Five patients with insulin allergy were desensitized with porcine insulin according to the method of Urbach and Gotlieb. The diagnosis of insulin allergy was based on clinical manifestations, positive skin tests, and, moreover, on positive Prausnitz-Kustner (P.K.) reactions in 2 cases. Successful desensitization was obtained in 3 cases.
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Immunologic Changes in Frail Older Adults
Translational medicine @ UniSa, 2014Several studies have shown a heightened inflammatory state in frail older adults, marked by high serum levels of interleukin-6 and C-reactive protein and an increased number of circulating leukocytes.
G. Wang, V. Casolaro
semanticscholar +1 more source
Penicillin desensitization: correlation of clinical and immunological events using an in vitro model
Clinical & Experimental Allergy, 1972SummaryA patient with actinomycosis was found to have immediate hypersensitivity to penicillin by previously described skin testing methods as well as by a recently described in vitro system utilizing rat peritoneal mast cells. Desensitization to penicillin became imperative, but in using the classical route (the intracutaneous route), systemic ...
S A, Gillman, J L, Korotzer, Z H, Haddad
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Transplant Immunology, 2011
Desensitization with IVIG and rituximab followed by transplantation with alemtuzumab or daclizumab induction is an effective clinical protocol. Here, we examined the effects of this protocol on immune cell number, T cell function by Cylex ImmuKnow®, CMV-specific CD8+ T cell (CMV-Tc) activity, total and viral-specific immunoglobulin levels and viral ...
Shili, Ge +12 more
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Desensitization with IVIG and rituximab followed by transplantation with alemtuzumab or daclizumab induction is an effective clinical protocol. Here, we examined the effects of this protocol on immune cell number, T cell function by Cylex ImmuKnow®, CMV-specific CD8+ T cell (CMV-Tc) activity, total and viral-specific immunoglobulin levels and viral ...
Shili, Ge +12 more
openaire +2 more sources
Transplantation Proceedings, 2019
Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation. Desensitization can improve transplantation rates in broadly sensitized kidney transplant recipients.
Ayse, Sinangil +6 more
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Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation. Desensitization can improve transplantation rates in broadly sensitized kidney transplant recipients.
Ayse, Sinangil +6 more
openaire +2 more sources
[New immunologic perspectives on specific desensitization].
Schweizerische medizinische Wochenschrift, 1978The development of objective techniques for the quantitative evaluation of synthesis and production of IgE in man and experimental animals and the sensitivity of basophils in interaction with allergen has made it possible to initiate studies on desensitization on a scientific and objective basis.
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The evolution of allergen immunotherapy from empirical desensitization to immunological treatment.
European annals of allergy and clinical immunology, 2013In its century-long history, allergen immunotherapy (AIT), has shown continuous evolution in terms of the materials and the treatment schedules used, the adequate duration, and the mechanisms of action underlying its clinical efficacy. The passage from the empirical phase of AIT to the era of evidence-based medicine (EBM) was associated with ...
Incorvaia, C +4 more
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Asfotase Alfa hypersensitivity: an outpatient 8-steps desensitization protocol
Immunologic research, 2021S. Scudu +5 more
semanticscholar +1 more source
Desensitization to natalizumab: clinical and immunological observations
Multiple Sclerosis Journal, 2012Giuseppe, Ribizzi +8 more
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