Results 221 to 230 of about 469,584 (272)

Induction of immunologic tolerance: desensitization to occupational allergens.

Journal of Allergy and Clinical Immunology, 1986
Contact sensitivity is a major cause of skin disease and industrial morbidity. The incidence of industrial dermatitis in a number of industries is listed in Table I. The purpose of this investigation was to develop a means of specifically suppressing the development of contact sensitivity to simple chemicals with a common exposure in industry. A simple
J. Turk, D. Parkers, P. Long, J. E. Bull
semanticscholar   +3 more sources

Overcoming Immunologic Barriers to Kidney Transplantation: Desensitization and Paired Donation

Current Surgery Reports, 2016
Renal transplantation offers a significant survival benefit over dialysis for patients with end-stage renal disease. Furthermore, transplantation with a living donor kidney offers superior survival when compared to a deceased donor. However, supply of transplantable kidneys continues to fall short of demand; living donation offers a solution to help ...
L. A. Allen, J. Locke
semanticscholar   +2 more sources

Outcome of Desensitization Therapy in Immunologically High-Risk Kidney Transplantation: Single-Center Experience.

Transplantation Proceedings, 2019
AIM Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation.
A. Si̇nangi̇l, Z. Ucar, Y. Koc, S. Barlas, Sana Abouzahir, S. T. Ecder, E. B. Akin   +6 more
semanticscholar   +3 more sources

Outcomes Following Flow-Cytometry Crossmatch-Positive Lung Transplants Managed With Peri-Operative Desensitization.

American Journal of Transplantation, 2023
Our program previously reported successful outcomes following virtual crossmatch (VXM)-positive lung transplants managed with peri-operative desensitization, but our ability to stratify their immunologic risk was limited without flow-cytometry crossmatch
M. Aversa, J. Kiernan, T. Martinu, Christopher J. Patriquin, D. Barth, Qixuan Li, E. Huszti, R. Ghany, M. Cypel, S. Keshavjee, L. Singer, K. Tinckam   +11 more
semanticscholar   +1 more source

First successful concomitant therapy of immune tolerance induction therapy and desensitization in a CRIM-negative infantile Pompe patient

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2021
Objectives Enzyme replacement therapy (ERT) with alglucosidase alfa (rhGAA) has changed the fatal course of infantile Pompe disease, however, development of anti rhGAA antibodies and infusion-associated reactions (IAR) restrict the tolerability and ...
Merve Emecen Şanlı, H. I. Ertoy Karagol, A. Kılıç, E. Aktaşoğlu, A. Inci, I. Okur, F. Ezgu, L. Tumer   +7 more
semanticscholar   +1 more source

Is ‘Desensitization’ for Ragweed Hay Fever Immunologically Specific?

International Archives of Allergy and Immunology, 1972
Cell reactivity (the peak percentage release of histamine) to ragweed antigen E and timothy pollen extract was studied in the leukocytes of children chosen for clinical ragweed sensitivity and treated with that antigen. At the beginning of therapy all children had responded to antigen E with >50% histamine release.
L M, Lichtenstein, D A, Levy
openaire   +2 more sources

Successful desensitization and early outcomes in two highly sensitized living-related kidney transplant recipients at IBN Sina Teaching Hospital, Sirte, Libya

World Journal of Advanced Research and Reviews
Highly sensitized kidney transplant candidates face significant immunologic barriers due to high donor-specific antibody (DSA) titers. This study reports the first two highly sensitized living-related kidney transplant recipients successfully ...
Mohamed Aboalgasem, Omran Aburqiqa, E. M. Emtair, Ali Khalifa Eljerroshi, Gadalla Diryag, Muammar Makhlouf, Ali Aboubakr F. Abd Alraheem, I. Kawalit   +7 more
semanticscholar   +1 more source

Immunological aspects of oral desensitization in food allergy.

Digestive diseases and sciences, 2000
IMMUNOLOGY ASPECTS OF ORAL DESENSITIZATION IN FOOD ...
Nucera, Eleonora, Schiavino, Domenico, D'Ambrosio, Cristiana, Stabile, Achille, Rumi, Carlo, Gasbarrini, Giovanni Battista, Patriarca, Giampiero   +6 more
openaire   +4 more sources

Long-term IgE immunological tolerance to peanut allergens: An alternative to Noon’s daily desensitization paradigm

Cellular Immunology, 2022
Herein, we show that profound afferent long-term peanut-allergen-specific IgE immunological tolerance for 3 to 9 months induced sustained unresponsiveness (SU) in naïve or peanut-sensitized rodents after peanut allergen immunization. Rodents were vaccinated sublingually with a peanut allergen extract or recombinant peanut allergen in chenodeoxycholate (
Swey-Shen Chen, David Lee, Hailan Zhang, Xi-Hua Cao, Kevin DuPrez   +4 more
openaire   +2 more sources

Insulin allergy. Clinical and immunological effects of specific desensitization

Acta Diabetologica Latina, 1969
Five patients with insulin allergy were desensitized with porcine insulin according to the method of Urbach and Gotlieb. The diagnosis of insulin allergy was based on clinical manifestations, positive skin tests, and, moreover, on positive Prausnitz-Kustner (P.K.) reactions in 2 cases. Successful desensitization was obtained in 3 cases.
openaire   +2 more sources