Results 41 to 50 of about 1,693 (178)

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

open access: yesAdvanced Materials, Volume 38, Issue 2, 8 January 2026.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal   +9 more
wiley   +1 more source

Sociologia del desenvolupament i límits ecològics [PDF]

open access: yesPapers. Revista de Sociologia, 1990
La interpretació convencional del canvi social contemporani depèn de la sociologia del desenvolupament o modernització, la qual és, en gran manera, un corol·lari de la teoria econòmica del creixement. Les crítiques al creixement fetes pels economistes ecològics (Georgescu-Roegen, Daly i altres) tenen, en conseqüència, diverses implicacions per a la ...
openaire   +4 more sources

Material Customized Toolpath Generation for the Near‐Net Shape Repair Manufacturing of Wear‐Damaged Gear Teeth

open access: yesJournal of Engineering, Volume 2026, Issue 1, 2026.
The manufacturing industry increasingly relies on laser metal deposition (LMD) for gear repair and manufacturing. This paper studies the repair process of a gear tooth, starting with the design and milling of a groove that serves as the substrate to rebuild the tooth.
Igor Ortiz   +5 more
wiley   +1 more source

El govern d'Internet

open access: yesIDP, 2006
L'escrit planteja una anàlisi de la temàtica del govern d'Internet, des del fenomen de la societat de la informació, en què l'eix bàsic del desenvolupament de polítiques ha d'estar basat en l'ésser humà.
Erick Iriarte
doaj   +1 more source

Sarcopenic Obesity and Longitudinal Trajectories on Cognitive Performance and Subtle Cognitive Impairment Over 6 Years in Older Adults

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Sarcopenic obesity has been suggested as a potential risk factor for cognitive decline; however, few prospective studies have been conducted to test this hypothesis. We aimed to assess the relationship between baseline sarcopenic obesity and 6‐year trajectories of cognitive performance and subtle cognitive impairment in older adults.
Héctor Vázquez‐Lorente   +19 more
wiley   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

open access: yesMolecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente   +5 more
wiley   +1 more source

Persistence of Causal Illusions After Extensive Training

open access: yesFrontiers in Psychology, 2019
We carried out an experiment using a conventional causal learning task but extending the number of learning trials participants were exposed to. Participants in the standard training group were exposed to 48 learning trials before being asked about the ...
Itxaso Barberia   +3 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, Volume 599, Issue 22, Page 3174-3195, November 2025.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

La gestió del coneixement en les organitzacions educatives

open access: yesRevista Catalana de Pedagogia, 2012
L'aparició i el desenvolupament de nous entorns de treball i aprenentatge són cada vegada més habituals en la societat del coneixement. En aquest context, la gestió del coneixement ha esdevingut ràpidament una estratègia fonamental per millorar els ...
David Rodríguez-Gómez
doaj  

Aprenentatge mòbil de llengües basat en criteris pedagògics

open access: yes@tic: Revista d'Innovació Educativa, 2015
El MALL (Mobile Assisted Language Learning) aporta una immensa quantitat d'aplicacions d'aprenentatge de llengües. En aquest context cal que el triple procés d'anàlisi, avaluació i desenvolupament d'aplicacions de MALL compleixi amb dues premisses ...
Rafael Seiz Ortiz
doaj   +1 more source

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