Results 31 to 40 of about 480,816 (130)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

DESENVOLVIMENTO DE SIG 3D COM OPENSOURCE PARA A ÁREA DE DISTRIBUIÇÃO DE ENERGIA ELÉTRICA

Revista Brasileira de Cartografia, 2011
Este artigo tem por objetivo a descrição do desenvolvimento de um projeto de SIG 3D com uma nova concepção, a qual integra a visão 2D tradicional, a visão 3D e a visão do Diagrama Unifilar (DU), este último básico das aplicações da distribuição de ...
Marcelo Antonio Nero, Nelkis de la Orden Medina, Ricardo Luis Guimarães dos Santos, Rodrigo Amaral Lapa, Sérgio Ferreira da Silva, João Paulo Müller da Silva, Christiane Regina Soares Brazil   +6 more
doaj  

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

Combined use of ELISA and Western blot with recombinant N protein is a powerful tool for the immunodiagnosis of avian infectious bronchitis

Virology Journal, 2018
Background The avian infectious bronchitis virus (IBV) remains a significant source of loss in the poultry industry and early diagnosis is required to prevent the disease from spreading.
Paula Fonseca Finger, Michele Soares Pepe, Luana Alves Dummer, Carolina Georg Magalhães, Clarissa Caetano de Castro, Silvia de Oliveira Hübner, Fábio Pereira Leivas Leite, Giseli Aparecida Ritterbusch, Paulo Augusto Esteves, Fabricio Rochedo Conceição   +9 more
doaj   +1 more source

Tecnologia social: uma estratégia para o desenvolvimento [PDF]

, 2004
Esta publicação apresenta reflexões de diversos representantes de instituições governamentais, do terceiro setor, da sociedade civil e de universidades sobre o tema da Tecnologia ...
Antonio E. Lassance, Jr., Claiton José Mello, Eduardo José Siqueira Barbosa, Flávio Cruvinel Brandão, Henrique Tahan Novaes, Jacqueline Rutkowski, Jacques De Oliveira Pena, Juçara Santiago Pedreira, Ladislau Dowbor, Paul Singer, Renato Dagnino, Sidney Lianza, Silvio Caccia Bava, Sonia Maria Portella Kruppa   +13 more
core  

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Proposal for Safety Classification of SSC for Land-Based Facilities to Support Nuclear-Powered Submarines

Brazilian Journal of Radiation Sciences
The design of land facilities to support nuclear-powered submarines involves complex regulatory challenges due to the unique combination of nuclear, military, and naval aspects.
Douglas Brandão Baroni, Hélio Massaharu Murata, Fagner Chagas Rother, Anelise Ruzzarin, William Henrique Silva Profeta, Sad Sandrini Borsoi, Eduardo Ascenso Reis Ribeiro, Luana Soares Jorge   +7 more
doaj   +1 more source

Desenvolvimento Tecnológico e as Relações Internacionais na Tríplice Fronteira [PDF]

, 2019
Artigo apresentado como trabalho de conclusão de curso da Especialização de Relações Internacionais Contemporâneas pela Universidade Federal da Integração Latino-Americana (UNILA)Este artigo analisa as demandas tecnológicas da região da Tríplice ...
Gomes, Regean Carlos Alves
core  

Multifunctional Alginate‐Based Films Reinforced With Ag‐ZnO/AgO/TiO2 Nanocomposites for Advanced Packaging and Biomedical Applications

Advanced Materials Interfaces, EarlyView.
Biodegradable polymeric films incorporated with a synergistic blend of metallic nanocomposites are developed and characterized. The films exhibit enhanced antibacterial activity against foodborne pathogens, demonstrating their potential as active materials for food packaging.
Adriana Dos Santos Silva, Davi Porfírio Da Silva, Alysson Nogueira Magalhães, Marcos Vinícius Dias Vermelho, Ângelo Márcio Leite Denadai, Anielle Christine Almeida Silva   +5 more
wiley   +1 more source