Results 141 to 150 of about 262,791 (308)

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Tracking the impact of climate factors on vegetation dynamics across the Alashan Plateau semi desert ecoregion [PDF]

Computational Ecology and Software
Several studies have demonstrated global climate change, which has happened worldwide; it significantly impacts terrestrial ecosystems. Studying vegetation phenology can provide insight into the impact of climate changes on ecosystems.
SeyedOmid Reza Shobairi, Samira Hemmati Roudbari, Qirghizbek Ayombekov, et al.   +2 more
doaj  

Dust Intensity Across Vegetation Types in Mongolia: Drivers and Trends

Remote Sensing
Dust storms, characterized by their rapid movement and high intensity, present significant challenges across atmospheric, human health, and ecological domains.
Chunling Bao, Yonghui Yang, Hasi Bagan, Qinxue Wang, Terigelehu Te, Bayarsaikhan Uudus, Mei Yong, Tanghong Liao   +7 more
doaj   +1 more source

The association between airborne pollen monitoring and sensitization in the hot desert climate. [PDF]

Clin Transl Allergy, 2020
Al-Nesf MA, Gharbi D, Mobayed HM, Dason BR, Mohammed Ali R, Taha S, Tuffaha A, Adeli M, Sattar HA, Trigo MDM.   +9 more
europepmc   +1 more source

Garbage Beam [PDF]

, 2017
Located in a hot desert climate area prone to strong winds, Egypt is made up of many homes with little to no roofing leaving civilians exposed to the harsh elements.
Back, Paula, Murillo, Mariela
core   +1 more source

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Calculation and characteristic analysis of water vapor content in the north slope of the Middle Kunlun Mountains

暴雨灾害
The water vapor changes in arid areas could affect the structure and evolution of water resource systems in their surrounding areas. Based on the precipitable atmospheric water vapor (GPS-PWV) of 4 ground-based GPS stations, the observation data of 2 ...
Jing LIU, Lianmei YANG, Junjiang LI, Yuling GUO, Aqiao LI   +4 more
doaj   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems

Advanced Science, EarlyView.
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li, Mingyu Xie, Nan Jia, Li‐Dong Mo, Qiang Yu, Fanjiang Zeng, Xiangyi Li   +6 more
wiley   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source