Results 31 to 40 of about 26,510 (265)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

An Optimal Air-Conditioner On-Off Control Scheme under Extremely Hot Weather Conditions

Energies, 2020
Being reliant on Air Conditioning (AC) throughout the majority of the year, desert countries with extremely hot weather conditions such as Qatar are facing challenges in lowering weariness cost due to AC On-Off switching while maintaining an adequate ...
Mohammed Al-Azba, Zhaohui Cen, Yves Remond, Said Ahzi   +3 more
doaj   +1 more source

Simulated climate effects of desert irrigation geoengineering [PDF]

Scientific Reports, 2017
AbstractGeoengineering, the deliberate large-scale manipulation of earth’s energy balance to counteract global warming, is an attractive proposition for sparsely populated deserts. We use the BNU and UVic Earth system models to simulate the effects of irrigating deserts under the RCP8.5 scenario.
Wei Cheng, John C. Moore, Long Cao, Duoying Ji, Liyun Zhao   +4 more
openaire   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Machine learning shows a limit to rain-snow partitioning accuracy when using near-surface meteorology

Nature Communications
Partitioning precipitation into rain and snow with near-surface meteorology is a well-known challenge. However, whether a limit exists to its potential performance remains unknown.
Keith S. Jennings, Meghan Collins, Benjamin J. Hatchett, Anne Heggli, Nayoung Hur, Sonia Tonino, Anne W. Nolin, Guo Yu, Wei Zhang, Monica M. Arienzo   +9 more
doaj   +1 more source

Enhancing heat efficiency in arid environments using a PVT collector for revealed facade shelter

Journal of Thermal Engineering
In Ouargla neighboring (Algeria), the harsh climate conditions and the isolation of agricultural areas pose some difficulties for developing agriculture. For lightening climatic constraints, thermal comfort in farmer homes is required.
Mohamed Cherif BENZID, Boubekeur DOKKAR, Abdelghani BOUBEKRI   +2 more
doaj   +1 more source

Exploring the Synergies between Urban Overheating and Heatwaves (HWs) in Western Sydney

Energies, 2020
There is no consensus regarding the change of magnitude of urban overheating during HW periods, and possible interactions between the two phenomena are still an open question, despite the increasing frequency and impacts of Heatwaves (HW). The purpose of
Hassan Saeed Khan, Riccardo Paolini, Mattheos Santamouris, Peter Caccetta   +3 more
doaj   +1 more source

Brief Communication: Early season snowpack loss and implications for oversnow vehicle recreation travel planning [PDF]

The Cryosphere, 2019
Oversnow vehicle recreation contributes to rural economies but requires a minimum snow depth to mitigate negative impacts on the environment. Daily snow water equivalent (SWE) observations from weather stations in the Lake Tahoe region (western USA) and ...
B. J. Hatchett, B. J. Hatchett, H. G. Eisen   +2 more
doaj   +1 more source

Present Situation, Problems and Development Strategy for Comprehensive Control in Desert Regions of China in New Era

Shuitu baochi tongbao, 2022
[Objective] The present situation, problems, and development strategy for comprehensive control in the desert regions of China in the context of international and national conditions, science and technology, and climate change in a new era were studied ...
Xiao Jianhua, Qu Jianjun, Yao Zhengyi, Pang Yingjun   +3 more
doaj   +1 more source

Climate forcing and desert malaria: the effect of irrigation [PDF]

Malaria Journal, 2011
Abstract Background Rainfall variability and associated remote sensing indices for vegetation are central to the development of early warning systems for epidemic malaria in arid regions. The considerable change in land-use practices resulting from increasing irrigation in recent decades raises important questions on ...
Andrés Baeza, Menno J. Bouma, Andy Dobson, R. C. Dhiman, H. C. Srivastava, Mercedes Pascual   +5 more
openaire   +5 more sources