Results 71 to 80 of about 1,016,311 (303)
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Punishing Artificial Intelligence: Legal Fiction or Science Fiction [PDF]
, 2019 Whether causing flash crashes in financial markets, purchasing illegal drugs, or running over pedestrians, AI is increasingly engaging in activity that would be criminal for a natural person, or even an artificial person like a corporation. We argue that
Abbott, Ryan, Sarch, Alexander
core +2 more sources
Advanced Science, EarlyView.A CoCrFeNiTa0.4 eutectic high‐entropy alloy achieves a near‐theoretical yield strength of 2.6 GPa with 13.6% plasticity. This breakthrough stems from a hierarchical nanostructure (FCC‐Laves lamellae with L12/D022 precipitates), which alleviates the inter‐phase modulus/hardness mismatch through synergistic strengthening and toughening, guiding the ...
Yusha Luo +10 more
wiley +1 more source
Hildegard as a Mystic and her Place in the Christian Thought (PhD. Dissertation)
ULUM, 2019 Mysticism, visions, feminism, music, herbal medicine…Hildegard of Bingen (1098-1179) have been identified with these notions. Because she has influenced Christianity until today with her extraordinary visions and various works about God, man, cosmology ...
Halil Temiztürk
doaj +3 more sources
Journal of Architecture, Art & Humanistic Science, 2016 The importance of the study of Islamic Heritage In being an “outstanding balance and inventory” Which is characterized by stability and continuity together, And collects in itself spiritual and aesthetic value, In addition to being the fact that concrete
Sherif Hussien
doaj +1 more source
Advanced Science, EarlyView.A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source
Ungaretti and the Invention of the Desert
Teoliterária: Revista Brasileira de Literaturas e Teologias, 2015 The desert is the land of the Profets and its void delimits a space of infinity possibilites. The presence of this space in the italian poetry is considerable.
Daniel del Percio
doaj
Advanced Science, EarlyView.A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo +8 more
wiley +1 more source
Borderless Boundaries – as Means of Death and Life: Wilderness Portraits in Patristic and Rabbinic Literature [PDF]
, 2015 This study examines the role played by environmental representation of an apparent borderless boundary, the desert, as presented in Scripture – the Hebrew Bible / First Testament.
Maoz, Daniel
core +2 more sources