Results 231 to 240 of about 827 (292)

Glycosylation of the murine cardiac channel TRPM4 is altered by the pathogenic p.I376T variant

open access: yesExperimental Physiology, EarlyView.
Abstract TRPM4 is a calcium‐activated, voltage‐modulated, non‐selective cation channel expressed in various tissues, including the heart. In 2016, we reported on a large French family with progressive heart block type I carrying the variant TRPM4 p.I376T.
Sabrina Guichard   +6 more
wiley   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma   +12 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Geospatial analysis of Plasmodium falciparum serological indicators: school versus community sampling in a low-transmission malaria setting. [PDF]

open access: yesBMC Med
Jaramillo-Underwood A   +18 more
europepmc   +1 more source

Exercise training prior to and during cancer in mice preserves muscle mass, reduces tumour weight and suppresses molecular mediators of cachexia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend PoWeR training (11.5 weeks of voluntary wheel running with progressively increased resistance) before and during cancer attenuates muscle loss, limits tumour growth, drives a transition toward a more oxidative muscle phenotype (IIB‐to‐IIA shift), downregulates cachexia‐associated pathways and enhances mitochondrial performance in
Stavroula Tsitkanou   +13 more
wiley   +1 more source

Root trait dynamics of historical canola varieties under low and high nitrogen supply

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Nitrogen fertilizer is a major input cost in crop production, making it crucial to enhance nitrogen use efficiency (NUE) to reduce fertilizer dependence without compromising yields. Root system architecture (RSA) is a key determinant of nutrient acquisition, particularly under nutrient‐limited conditions.
Shankar Pahari, Raju Soolanayakanahally
wiley   +1 more source

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