Results 51 to 60 of about 57,774 (296)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Streptococcus pneumoniae Is Desiccation Tolerant and Infectious upon Rehydration

mBio, 2011
Streptococcus pneumoniae (pneumococcus) is a frequent colonizer of the nasopharynx and one of the leading causative agents of otitis media, pneumonia, and meningitis. The current literature asserts that S.
Rebecca L. Walsh, Andrew Camilli
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Understanding desiccation tolerance using the resurrection plant Boea hygrometrica as a model system

Frontiers in Plant Science, 2013
Vegetative tissues of Boea hygrometrica, a member of the Gesneriaceae family, can tolerate severe water loss to desiccated state and fully recover upon rehydration. Unlike many other so called resurrection plants, the detached leaves of B.
Jayeeta eMitra, Jayeeta eMitra, Guanghui eXu, Bo eWang, Meijing eLi, Xin eDeng   +5 more
doaj   +1 more source

Tolerance to freezing stress in cyanobacteria, Nostoc commune and some cyanobacteria with various tolerances to drying stress [PDF]

, 2004
Tolerance to and effects of the freezing stress in a desiccation-tolerant, terrestrial cyanobacterium, Nostoc commune, in cultivated strains of N. commune, and in desiccation-sensitive species, Synechocystis sp.
Hiroyuki Koike, Kazuhiko Satoh, Manabu Hirai, Satoru Tuzi, Yasuhiro Kashino, Yufang Lin   +5 more
core   +1 more source

Desiccation tolerance: From genomics to the field [PDF]

, 2010
Desiccation tolerance is defined as the ability to survive the removal of all, or almost all the cellular water without irreversible damage. It confers to dried organisms the ability to survive extreme conditions of the environment and to stay alive in a
J. Buitink, O. Leprince
core   +4 more sources

Desiccation tolerance of cambuci seeds

Comunicata Scientiae, 2020
This work aimed to evaluate the interference of seed desiccation on the occurrence of root protrusion and the formation of normal cambuci seedlings. Seeds were obtained from mature fruits collected from adult plants and submitted to oven drying with forced air circulation at 30±2°C in order to obtain different water contents.
Marcelo Brossi Santoro, Bruna do Amaral Brogio, Victor Augusto Forti, Ana Dionísia da Luz Coelho Novembre, Simone Rodrigues da Silva   +4 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? [PDF]

, 2015
This work was financially support by a Marie Curie Initial Training Network grant, “Understanding the evolutionary origin of biological diversity” (ITN-2008–213780 SPECIATION), grants from the Academy of Finland to A.H.
A Hoikkala, A Laiho, A Martin, A Sasson, AA Hoffmann, AL Majumder, AR McCune, B Katz, BJ Sinclair, C Canestro, CJ Reaume, CP Downes, D Arbuthnott, D Bell-Pedersen, D J Parker, DW Huang, DW Huang, FA Loewus, H Colinet, H Colinet, HA MacMillan, J Overgaard, J Zhang, JR Hazel, K Xu, KB Storey, KY Xu, L Kivivuori, L Vesala, L Vesala, L Vesala, LH Throckmorton, M G Ritchie, M Kankare, M Kim, M Reis, M Watanabe, M Watanabe, MC Magnone, MD Robinson, MD Robinson, MJ Fitzpatrick, MK Jones, MV Rockman, NM Teets, PR Senthilan, PW Hochachka, R David, R Morales-Hojas, R Niwa, RE Lee, RE Lee, RM Robich, RW Salt, S Anders, S Fowler, S Sahar, S Tweedie, V Kellermann, V Kostal, V Koštál, V Koštál, Vr Koštál, W Block, W Huang, WJ Heitler, WL Shen, X Huang, XL Guan, Y Benjamini, ZD Liu   +70 more
core   +2 more sources

AMPHIBIAN DISTRIBUTION IN THE GEORGIA SEA ISLANDS: IMPLICATIONS FROM THE PAST AND FOR THE FUTURE [PDF]

, 2020
We summarized amphibian distributions for 12 coastal islands in Georgia, USA. Occurrence among islands was correlated with life history traits, habitats, island size, distance to other islands, and island geological age.
Carroll, C. Ron, Jordan, Thomas R., Mu, Lan, O'Hare, Nancy K.   +3 more
core   +2 more sources