Results 121 to 130 of about 4,637,291 (273)

Artists’ books in HE teaching and learning [PDF]

open access: yes, 2012
Learning resource, teaching collection, study collection, research collection or special collection: a historical collection of artists’ books like that at Chelsea College of Art & Design Library can (and probably, has) been used and referred to in all ...
Grandal Montero, Gustavo
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Advancing LED technology: the FDCSP element’s breakthrough in mini and micro-LED packaging and backlight module enhancement

open access: yesDiscover Nano
In this research, we introduce an advanced methodology for the calculation of bulk light sources tailored for free-form surface design, focusing on the principle of energy conservation.
Jo-Hsiang Chen   +5 more
doaj   +1 more source

Integrating Design for Manufacturing and Assembly Principles in Modular Home Construction: A Comprehensive Framework for Enhanced Efficiency and Sustainability

open access: yesBuildings
The growing demand for sustainable and efficient construction practices has led to an increased interest in modular construction, with design for manufacture and assembly emerging as a pivotal approach.
Sadaf Montazeri   +3 more
doaj   +1 more source

Welcoming Workplace: Rapid Design Intervention to Determine the Office Environment Needs of Older Knowledge Workers [PDF]

open access: yes, 2010
This book chapter details the context, methods, findings and implications of the Welcoming Workplace project (RCA, 2006–8), which was part of Phase 2 of the Designing for the 21stCentury Research Programme (AHRC-EPSRC), directed by Professor Tom Inns ...
Bichard, Jo-Anne, Myerson, Jeremy
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Dynamic models for a heat-led organic rankine cycle [PDF]

open access: yes, 2013
Drawn by the benefits of de-centralised and renewable power supply, over 150 Organic Rankine Cycles (ORC), in a range from 400kWel to 2MWel, have been installed in Central Europe. The majority of modules are biomass fired and heat-led by district heating
Eicker, Ursula   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Transformation of Family-Owned Enterprises into Design-Intensive Firms

open access: yesForum Scientiae Oeconomia
This study examines how family-led small and medium-sized enterprises (SMEs) with little or no design experience are transforming into design-intensive firms.
Satoru Goto
doaj   +1 more source

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