Results 191 to 200 of about 1,705,946 (235)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The MILEPOST Framework for Integrating mHealth Into Community-Driven Interventions: Lessons Learned From a Human-Centered Design Approach in Rural Uganda. [PDF]

Glob Health Sci Pract
Schwab J, Wachinger J, Nabiryo M, Cazier J, Wanyana J, Mayombwe K, Okou E, Oloka D, Ntambara JB, Munana R, Weswa I, Sekitoleko I, Basenero A, Ingenhoff R, Favaretti C, Pillai VS, Bärnighausen T, Sudharsanan N, Kalyesubula R, Nalwadda C, McMahon SA.   +20 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A study of the effect of peer-led instruction on the improvement of swimming skills of university students. [PDF]

Front Psychol
Xie D, Song W, Wang L, Lin X.
europepmc   +1 more source

A pharmacist-led, workplace-based educational intervention informed by behavioral science to influence antimicrobial prescribing in Japan. [PDF]

Korean J Med Educ
Masuda K, Gomi H, Tanuma J, Hiramatsu T, Sato T, Takaya S, Kato Y, Matsumoto T.   +7 more
europepmc   +1 more source

When "Integration" fails to address loneliness: interventional challenges of parent-led organizations for autistic children's social/emotional loneliness and health equity in China. [PDF]

BMC Public Health
Wang X, Guo X.
europepmc   +1 more source

STFM Launches Scholarship Academy Task Force. [PDF]

Ann Fam Med
Abuel M.
europepmc   +1 more source