Results 81 to 90 of about 4,637,291 (273)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Interdisciplinary Urban Interventions: Fostering Social Justice Through Collaborative Research-Led Design in Architectural Education

open access: yesArchitecture
This study aims to examine how interdisciplinary urban interventions within architectural education can effectively address social justice issues.
Asma Mehan, Natalia Dominguez
doaj   +1 more source

The influence of serifs on 'h' and 'i': useful knowledge from design-led scientific research [PDF]

open access: yes, 2014
The typographical naivety of much scientific legibility research has caused designers to question the value of the research and the results. Examining the reasons underlying this questioning, the paper discusses the importance of designers being more accepting of scientific findings, and why legibility investigations have value.
Beier, Sofie, Dyson, Mary C.
openaire  

Design bugs out: a real world investigation of hospital bedside chairs and commodes [PDF]

open access: yes, 2009
This paper was presented at the the 17th World Congress on Ergonomics (IEA’09) in August 2009, Beijing, China.Healthcare Associated Infections (HCAIs) can affect both patients and healthcare workers.
Dong, H, McGinley, C
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

‘One big wheel’: young people’s participation in service, design, development and delivery (Sharing our experience, Practitioner-led research 2008-2009; PLR0809/080) [PDF]

open access: yes, 2009
How do professionals and agencies seek the views of young people moving from participation to the implementation of service design and delivery? The research involved six white British young people from the Camborne, Pool and Redruth (CPR) area of ...
James, Natasha
core  

Expanding horizons:Engaging students with empathic thinking [PDF]

open access: yes, 2019
Young student designers have little experience with populations unlike themselves. This can present challenges when project briefs require them to design for people with different life experiences and abilities.
Ball, Tim   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Investigating information systems with mixed-methods research [PDF]

open access: yes, 2011
Mixed-methods research, which comprises both quantitative and qualitative components, is widely perceived as a means to resolve the inherent limitations of traditional single method designs and is thus expected to yield richer and more holistic findings.
Annansingh, F.   +2 more
core  

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