C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Reform and practice of the cross-integration teaching model: A case study of visual communication design. [PDF]
Wang J, Liu H.
europepmc +1 more source
A popular description of the Natal Ferns : designed for the use of amateurs, &c
John Medley Wood
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Discussion: “Problems Encountered in the Design and Operation of Impulse Turbines” (Quick, Ray S., 1940, Trans. ASME, 62, pp. 15–20) [PDF]
J. D. Galloway
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
User Experience of Older Adults With an Age-Friendly Transportation Planning E-Tool: Scoping Review.
Bahrampoor Givi S+3 more
europepmc +1 more source
Design optimization of a novel dual-skewed Halbach-array double-sided axial flux permanent magnet motor for electric vehicles. [PDF]
Srikhumphun P+4 more
europepmc +1 more source
Experiment designed to show the relationship between soil and changes in the vegetational cover. [PDF]
Donald P. Duncan, R. W. Varner
openalex
Some Aspects of the Analysis of Factorial Experiments in a Completely Randomized Design [PDF]
M. B. Wilk, Oscar Kempthorne
openalex +1 more source