Results 261 to 270 of about 30,963,012 (385)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The use of patient and public involvement and engagement in the design and conduct of implementation research: a scoping review. [PDF]

Implement Sci Commun
Mathieson A, Brunton L, Wilson PM.
europepmc   +1 more source

Motor Vehicles and Motors: their Design, Construction and Working by Steam, Oil and Electricity

, 1907
W. Worby Beaumont
openalex   +2 more sources

Design of Surface Combustion Appliances. [PDF]

, 1913
Charles E. Lucke
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Structural optimization, compressive strength analysis, and application exploration of triply periodic minimal surfaces (TPMS) in interior design. [PDF]

Sci Rep
Huang Y, Zhai L.
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Enhancing access to nephrology care: telenephrology dashboard optimization via human-centered design. [PDF]

BMC Nephrol
Swee M, Kumar B, Sanders ML, Thumann A, Phisitkul K, Griffin BR, Yamada M, Sambharia M, Vaughan-Sarrazin M, Reisinger HS, Dixon BS, Jalal DI.   +11 more
europepmc   +1 more source

The Roentgen Rays in Medicine and Surgery as an Aid in Diagnosis and as a Therapeutic Agent. Designed for the Use of Practitioners and Students.

, 1902
Francis H Williams, Francis Henry Williams   +1 more
openalex   +2 more sources

An Induction Flowmeter Design Suitable for Radioactive Liquids [PDF]

, 1951
William G. James
openalex   +1 more source