Results 301 to 310 of about 30,963,012 (385)

Factors influencing critical thinking in simulation-based maternal-child nursing education among undergraduate nursing students: a mixed methods study. [PDF]

BMC Nurs
Nuampa S, Ratinthorn A, Tangsuksan P, Chalermpichai T, Kuesakul K, Ruchob R, Chanphong J, Buranasak J, Khadking N, Subsomboon K, Pangzup S, Sirithepmontree S, Hungsawanus P.   +12 more
europepmc   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Multifactor exploration and multi-objective optimization of trapezoidal threads. [PDF]

Sci Rep
Zhou Y, Yan Z, Zhou P, Zheng Y.
europepmc   +1 more source

Improved LARYNGOSCOPE BLADE designed for ease of manipulation and reduction of trauma

, 1958
D Bizzarri, Joseph G. Giuffrida
openalex   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Reducing risk of bias in interventional studies during their design and conduct: a scoping review. [PDF]

BMC Med Res Methodol
Ren Z, Webster AC, Hunter KE, Zhang J, Yao Y, Tan-Koay AG, Tan AC.   +6 more
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Customization of manual wheelchair components: a state-of-the-art review. [PDF]

J Neuroeng Rehabil
More S, Dunn M, Rios SA, McDonald R.
europepmc   +1 more source

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

FEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda, Hiroshi Iwakura, Takuya Ensho, Mika Bando‐Shimizu, Asako Doi, Norihiko Matsutani, Shuhei Morita, Hidefumi Inaba, Hiroyuki Ariyasu, Naoki Fukuda, Keiji Hayata, Toshiyasu Ojima, Masahiro Nishi, Taka‐aki Matsuoka, Hiroki Yamaue, Takashi Akamizu   +15 more
wiley   +1 more source

Integrating design thinking into dental education. [PDF]

Front Oral Health
Chuenjitwongsa S, Amir LR, Jessani A, Samaranayake LP, Osathanon T.   +4 more
europepmc   +1 more source