Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Use of design thinking to develop a benchmarking tool to assess documentation procedures in a hospital pharmacy aseptic compounding unit: a case study. [PDF]
Murphy N, Garvey E, Naughton BD.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Eddy current measurements of dielectric coating thickness on a weakly magnetic substrate within the medium frequency range. [PDF]
Halchenko VY +3 more
europepmc +1 more source
Automated modeling to high level-of-detail composite object using spatial BIM objects and properties. [PDF]
Lee JK, Cho D, Kim Y, Mo Y.
europepmc +1 more source
Development and validation of social compensation design scale for urban older users in the context of smart-home social media. [PDF]
Ma K +5 more
europepmc +1 more source
Research on road parametric modeling and dynamic lightweighting methods driven by BIM-GIS integration. [PDF]
Cao Y +5 more
europepmc +1 more source
Unlocking toughness in 3D-printed cement through bio-inspired designs: current status and future perspectives. [PDF]
Fan L +9 more
europepmc +1 more source

