Results 181 to 190 of about 636,549 (266)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Antenna Design and Construction of a Free-Pass System for Hi-Pass Type Ticket Gates in Subways for Transportation-Disadvantaged Individuals. [PDF]

Sensors (Basel)
Lee Y, Lee C, Yoon C, Kim W.
europepmc   +1 more source

The design and construction of reference pangenome graphs with minigraph. [PDF]

Genome Biol, 2020
Li H, Feng X, Chu C.
europepmc   +1 more source

Correction: Semantic and ontology-based analysis of regulatory documents for construction industry digitalization

Frontiers in Built Environment
Zarina Kabzhan, Alexandr Shakhnovich, Sergey Gorshkov, Yussuf Yemenov, Fedor Gorshkov, Nazym Shogelova   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Modularized Design and Construction of Tunable Microbial Consortia with Flexible Topologies. [PDF]

ACS Synth Biol
Chen X, He C, Zhang Q, Bayakmetov S, Wang X.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Design and construction of gradient coils for an MRI-guided small animal radiation platform. [PDF]

Heliyon
Grandinetti J, Zhong Y, Peng Y, Jia X.
europepmc   +1 more source