Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Numerical Investigation of Dynamic Wrinkling Behaviors in Stiff-Film/PDMS-Substrate Structure. [PDF]
Bi H, Li W, Wang L, Wang B.
europepmc +1 more source
Disseminated miliary lupus on the face: successful treatment with oral dapsone and topical metronidazole. [PDF]
Fernandes TRMO +4 more
europepmc +1 more source
Hole-Patterned Pellicles: A Structural Approach for Improved Extreme Ultraviolet Transmittance and Mechanical Behavior. [PDF]
Kim H +7 more
europepmc +1 more source
Crashworthiness Performance of Bamboo-Inspired 3D-Printed Tubes: Effects of Infill Pattern, Infill Ratio, Wall Thickness, and Inner Diameter. [PDF]
Albak Eİ.
europepmc +1 more source
A Low-Sidelobe Fully Metallic Ridge Gap Waveguide Antenna Array for W-Band Applications. [PDF]
Jiang H +6 more
europepmc +1 more source
Advanced RSM-Driven Optimisation for Enhancing the Mechanical Performance of FDM-Printed PETG: A Correlated Microstructural and Mechanical Property Investigation. [PDF]
Kumaresan R, Kanny K.
europepmc +1 more source

